Consumption of phytochemical-rich foods relates to the prevention chronic diseases. In this study we assessed dietary phytochemical index (PI) in metabolic parameters, liver enzymes, and severity fibrosis among nonalcoholic fatty disease patients. This cross-sectional was conducted on 210 patients with NAFLD. Fibrosis-4 (FLB4), score (NFS), FBS, lipids profile, AST, ALT, ALP, GGT were measured....

BACKGROUND Stearoyl-coenzyme A desaturase 1 (SCD1) catalyzes the limiting step of monounsaturated fatty acid synthesis in humans and is an important player in triglyceride generation. SCD1 has been repeatedly implicated in the pathogenesis of metabolic and inflammatory diseases. Therefore it is of great importance to determine SCD1 activity in human samples. In this study we aimed to evaluate a...

Emerging evidence from a number of laboratories indicates that humans have the ability to identify fatty acids in the oral cavity, presumably via fatty acid receptors housed on taste cells. Previous research has shown that an individual's oral sensitivity to fatty acid, specifically oleic acid (C18:1) is associated with body mass index (BMI), dietary fat consumption, and the ability to identify...

The aim of this study was to investigate the influence of fatty tissue layer on EMG signal parameters as a function of force level and type of muscle in young women. On the basis of body mass index (BMI) and the amount of fatty tissue (FT) 30 young women were divided into two equal groups: obese (O) and reference group (R). The EMG signal was measured on 5 levels of load from 2 muscles: palmari...

Murine thioglycollate-elicited peritoneal macrophages were cultured in the presence of a variety of fatty acids added as complexes with bovine serum albumin. All fatty acids tested were taken up readily by the cells and both neutral and phospholipid fractions were enriched with the fatty acid provided in the medium. This generated a range of cells enriched in saturated, monounsaturated or polyu...

Mechanisms responsible for alcohol-induced heart muscle disease have been difficult to elucidate partly because of previously obscure, demonstrable cardiac metabolism of ethanol. Recently, fatty acid ethyl esters were identified in our laboratory and found to be myocardial metabolites of ethanol. In the present study, they have been shown to induce mitochondrial dysfunction. Incubation of isola...

We investigated the effects of dietary trans fatty acids, PUFA, and SFA on body and liver fat content, liver histology, and mRNA of enzymes involved in fatty acid metabolism. LDL receptor knockout weaning male mice were fed for 16 wk with diets containing 40% energy as either trans fatty acids (TRANS), PUFA, or SFA. Afterwards, subcutaneous and epididymal fat were weighed and histological marke...