In this study, the determination of the efficiency of a pilot-scale fermentation process using corn steep liquor as a nitrogen source was attempted in order to produce lactic acid via batch culturing of Lactobacillus sp. RKY2. Using pure glucose, fermentation efficiency characteristics, such as final lactic acid, cell growth, yield, and productivity were not substantially influenced by the scal...

A previous study demonstrated that paper sludges with high ash contents can be converted to ethanol by simultaneous saccharification and fermentation (SSF) or simultaneous saccharification and cofermentation (SSCF). High ash content in the sludge, however, limited solid loading in the bioreactor, causing low product concentration. To overcome this problem, sludges were de-ashed before SSF and S...

The studies on the alcoholic fermentation with immobilized S. cerevisiae cells on alginate using a bioreactor with stirred beds of biocatalysts indicated that the diffusion inside the biocatalyst particles attenuates or avoids the inhibitory effects, preserving the microbial activity. Using a mathematical model adequate for ethanol formation in heterogeneous systems the kinetic parameters V, KI...

The bioconversion of environmental wastes into energy is gaining much interest in most developing and developed countries. current study concerned with the proper exploitation some industrial wastes. Cellulosic fiber waste was selected as a raw material for producing bioethanol an alternative source. A combination physical, chemical, enzymatic hydrolysis treatments applied to maximize concentra...

Substitution of fossil fuels with alternative energy carriers has become necessary due to climate change and fossil fuel shortages. Fermentation as a way of producing biohydrogen, an attractive and environmentally friendly future energy carrier, has captured received increasing attention in recent years because of its high H2 production rate and a variety of readily available waste substrates u...

Batch processes, such as fermenters, generally require high levels of consistency in their operation to ensure minimal losses of raw materials and product. Recent application studies have indicated that multivariate statistical technology can provide some support when trying to maintain consistent operation in complex batch processes. This paper aims to compare four different approaches to batc...

The Japanese fermented food Natto contains menaquinone 7 (MK7), which is known to increase bone mineral density and reduce bone fractures. Natto is traditionally produced via the solid state fermentation of soy beans by Bacillus subtilis natto. The aim of this study was to investigate the effects of static and dynamic solid state fermentation (SSF) on the production of MK7 using polenta (milled...

Cladospirone bisepoxide (1), a novel metabolite, was isolated from cultures of a fungus which was characterized as a coelomycete by the formation of pycnidia. By optimization of media and fermentation conditions, a titer of up to 1.5 g/liter on shake level and 1.16 g/liter on bioreactor scale could be achieved. The isolation of the compound was performed by solvent extraction of the culture bro...

A segregated model was proposed to investigate the inherent relationships between growth, substrate consumption, cell differentiation and product formation in a Bacillus subtilis fermentation producing heterologous amylase in a 22-l bioreactor. The segregated model includes three distinguishable cell states and the transition from vegetative phase to sporangium and finally to mature spore. An a...