sphingosine-1-phosphate (s1p) is a bioactive platelet-derived sphingolipid involved in regulation, proliferation, differentiation, hypertrophy and anti-apoptosis of cells and activation of satellite cells. the aim of the present study was to investigate s1p as a growth factor in response to resistance training in male wistar rats. 24 eight-week-old male wistar rats (190–250 gr.) were used in th...

1 Department of Animal Science, Faculty of Science and Technology, Aarhus University, P.O. Box 50, 8830 Tjele, Denmark; E-Mails: [email protected] (H.N.L.); [email protected] (K.E.B.K.) 2 Department of Food Science, Faculty of Life Science, University of Copenhagen, Rolighedsvej 30, DK-1958 Frederiksberg C, Denmark; E-Mail: [email protected] 3 Novozymes A/S, Krogshøjvej 36, DK-2...

Reconstruction following excision of tumors of the Achilles tendon poses a challenge to the treating surgeon. Described techniques for restoration of plantarflexion in the setting of an unrepairable tendon include the use allograft, autograft, tendon transfer, and free flap. In tumor surgery, options may be limited as total tendon resection may be necessary leaving little or no residual tendon ...

Yoshida N, Tsuchida Y. BMJ Case Rep 2017. doi:10.1136/bcr-2017-222231 Description A 37-year-old man presented to the emergency department with right lower limb pain after being hit by an excavator. His right ankle was swollen, but no open wounds were observed. Radiography and CT of the right ankle revealed a medial malleolus ankle fracture (figure 1A,B). During his treatment with osteosynthesis...

Candida albicans uses human complement regulators such as factor H and factor H-like protein 1 (FHL-1) for immune evasion. To define the whole panel of fungal complement-evasion molecules, C. albicans cell extract was absorbed to a factor H-coupled matrix. One 52-kDa protein was eluted and identified by mass spectrometry as glycerol-3-phosphate dehydrogenase 2 (Gpd2). Consequently, Gpd2 was rec...

Wolman disease; Familial hemophagocytic lymphohistiocytosis; Hepatomegaly; Splenomegaly; Fever Abstract Background: Familial hemophagocytic lymphohistiocytosis is a rare autosomal recessive disease that is usually evident in the first few months or years of life. Major signs and symptoms include hepatomegaly, splenomegaly, anemia, leucopenia or thrombocytopenias which resemble many inborn error...

RATIONALE The giant protein titin plays key roles in myofilament assembly and determines the passive mechanical properties of the sarcomere. The cardiac titin molecule has 2 mayor elastic elements, the N2B and the PEVK region. Both have been suggested to determine the elastic properties of the heart with loss of function data only available for the N2B region. OBJECTIVE The purpose of this st...

the purpose of this study was to investigate the effects of 8 weeks of endurance training (et) on ? -1a protein of pre-synaptic p-q-type calcium channels in fhl and soleus muscles of rats. 16 male wistar rats provided from razi institute, were randomly divided to 2 groups (control-sham; n=8 and endurance training; n= 8). training group performed 8 weeks (5 session/week) of endurance training on...