Thin sections (0.1-0.25 micron) of isolated chicken erythrocyte nuclei were examined at various tilt angles. Stereo pairs of electron micrographs document the parallel alignment of 25-nm chromatin fibers adjacent to the nuclear envelope, and demonstrate a fiber substructure consistent with close-packed arrays of nucleosomes.

We have developed a 7-core-fiber connector. To maintain both the ferrule floating mechanism and precise alignment around the ferrule axis, we employed Oldham's coupling mechanism inside the MUtype connector plug housing and realized an average attenuation of 0.13 dB and an average return loss of 46.8 dB.

A new epoxy-based ink is reported, which enables 3D printing of lightweight cellular composites with controlled alignment of multiscale, high-aspectratio fiber reinforcement to create hierarchical structures inspired by balsa wood. Young's modulus values up to 10 times higher than existing commercially available 3D-printed polymers are attainable, while comparable strength values are maintained.

Precision time synchronization between two remote sites is desired in many applications such as global positioning satellite systems, long-baseline interferometry, coherent radar detection and fundamental physics constant measurements. The recently developed frequency dissemination technologies based on optical fiber link have improved the transfer instability to the level of 10(-19)/day at rem...

OBJECTIVE To assess the potential of adipose-derived nucleated cell (ADNC) fractions to improve tendon repair in horses with collagenase-induced tendinitis. ANIMALS 8 horses. PROCEDURES Collagenase was used to induce tendinitis in the superficial digital flexor tendon of 1 forelimb in each horse. Four horses were treated by injection of autogenous ADNC fractions, and 4 control horses were i...

Objective(s): In this study, the effect of electrospun fiber orientation on proliferation and differentiation of mesenchymal stem cells (MSCs) was evaluated. Materials and Methods: Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polylactic acid (PLA), poly (vinyl alcohol) (PVA) and calcium carbonate nanoparticles (nCaP). The surface morphology of prepared nanofibrou...

Extracellular matrix (ECM) strongly influences cellular behaviors, including cell proliferation, adhesion, and particularly migration. In cancer, the rigidity of the stromal collagen environment is thought to control tumor aggressiveness, and collagen alignment has been linked to tumor cell invasion. While the mechanical properties of collagen at both the single fiber scale and the bulk gel sca...

Prior work by members of our laboratory and others demonstrated that adenovirus serotype 30 (Ad30), a group D adenovirus, exhibited novel transduction characteristics compared to those of serotype 5 (Ad5, belonging to group C). While some serotype D adenoviruses bind to the coxsackie-adenovirus receptor (CAR), the ability of Ad30 fiber to bind CAR is unknown. We amplified and purified Ad30 and ...

OBJECTIVES/HYPOTHESIS This investigation quantitatively characterizes the collagenous microstructure of human vocal ligament specimens excised postmortem from nonsmokers and smokers. STUDY DESIGN Retrospective cohort study. METHODS Second harmonic generation (SHG) imaging was performed at three anatomical locations of vocal ligament specimens: anterior, mid-membranous, and posterior regions...

The performance of very-high-speed integrated cir­ cuits and very-large-scale integrated circuits (VLSIC's) is impaired by limitations in the communi­ cation capacity among gates, chip, and boards.! Fi­ ber-optic interconnects are widely recognized as a po­ tential solution to this communication problem.27 However, no satisfactory means exists to couple a fiber to a detector on a VLSIC chip. We...