Introduction: Diffusion Tensor Imaging (DTI) is now a well-established scheme for analyzing neural pathways in the brain by means of streamline or probabilistic tractography. But DTI models the diffusion of water molecules by a Gaussian process, while the data captured by the diffusionweighted MRI (DW-MRI) could very well be non-Gaussian. To overcome this limitation, a High Angular Resolution D...

We present a general mathematical theory for the mechanical interplay in tissue-equivalents (cell-populated collagen gels): Cell traction leads to compaction of the fibrillar collagen network, which for certain conditions such as a mechanical constraint or inhomogeneous cell distribution, can result in inhomogeneous compaction and consequently fibril alignment, leading to cell contact guidance,...

In contrast to the more common Diffusion Tensor Imaging (DTI), High Angular Resolution Diffusion Imaging (HARDI) allows superior delineation of angular microstructures of brain white matter, and makes possible multiple-fiber modeling of each voxel for better characterization of brain connectivity. However, the complex orientation information afforded by HARDI makes registration of HARDI images ...

A set of edge-gated and center-gated plaques were injection molded with long carbon fiber-reinforced thermoplastic composites, and the fiber orientation was measured at different locations of the plaques. Autodesk Simulation Moldflow Insight (ASMI) software was used to simulate the injection molding of these plaques and to predict the fiber orientation, using the Anisotropic Rotary Diffusion an...

The evolution of texture was discussed during the formation of ultra-fine and nano grains in a magnesium alloy severely deformed through accumulative back extrusion (ABE). The microstructure and texture obtained after applying multiple deformation passes at temperatures of 100 and 250°C were characterized. The results showed that after single ABE pass at 100°C an ultrafine/nano grained microstr...

Cardiac and skeletal myosin assembled in the muscle lattice power contraction by transducing ATP free energy into the mechanical work of moving actin. Myosin catalytic/lever-arm domains comprise the transduction/mechanical coupling machinery that move actin by lever-arm rotation. In vivo, myosin is crowded and constrained by the fiber lattice as side chains are mutated and otherwise modified un...

OBJECTIVE To evaluate the structure-function relationships of the right ventricle (RV) and septum and determine if the helical ventricular band model would define fiber orientation for maximal force response. Implications were made for right ventricular function. METHODS The right ventricular free wall and biventricular septum were studied by inserting sonomicrometer crystals at different ang...

The common approach for simulating the evolution of fiber orientation during flow in concentrated suspensions is to use an empirically modified form of Jeffery’s equation referred to as the Folgar-Tucker model. Direct measurements of fiber orientation were performed in startup of shear flow for a 30 wt % short glass fiber-filled polybutylene terephthalate (PBT-30); a matrix that behaves similar...

The choice of local HARDI reconstruction technique is crucial for discerning multiple fiber orientations, which is itself of substantial importance for tractography, and reliable and accurate assessment of white matter fiber geometry. Due to the complexity of the diffusion process and its milieu, distinct diffusion compartments can have different frequency signatures, making the HARDI signal sp...