Uterine fibroids are quite common in women of the reproductive age group and as such commonly encountered in pregnancy. Though majority of these cases are asymptomatic, some are prone to developing complications and may end up having adverse outcomes in pregnancy. Management of these women with uterine fibroids presents its own challenges, especially in low-resource setting as in sub-Saharan Af...

Background/introduction In managing women with large uterine fibroids, GnRH agonists can be used to reduce fibroid volume and decrease vascularity to enhance treatment outcomes with MRgFUS. GnRH agonists have been shown to reduce fibroid volume by as much as 30-40%. The purpose of this study was to examine the responsiveness of fibroids to pre-treatment with a GnRH agonist in relation to their ...

Background: Fibroids are the commonest benign gynaecological tumors affecting only females and laparoscopic myomectomy is the modern management because of its various advantages, especially among women who still desire retention of their fertility. Materials and Methods: This is a retrospective review of 31 infertile patients who had laparoscopic myomectomy (LM) from January 2010 to December 20...

BACKGROUND Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) is a noninvasive uterine-preserving treatment alternative to hysterectomy for women with symptomatic uterine leiomyomas (fibroids). Uterine fibroids commonly occur, have a broad impact on women's health and lifestyle, continue to be the main indication for hysterectomy, and represent a costly public health burden. ...

Giant fibroids are known to arise from the uterus and very rarely from the broad ligament and that too after hysterectomy. We report an interesting case of broad ligament fibroid which developed after hysterectomy. The patient presented with incidental finding of a huge mass and pain in abdomen after 6 years of abdominal hysterectomy for multiple fibroids in uterus. Laparotomy was done which re...

Magnetic Resonance-guided focused Ultrasound Surgery (MRgFUS) is gaining popularity as an alternative to medical and surgical interventions in the management of symptomatic uterine fibroids. Studies have shown that it is an effective non-invasive treatment with minimal associated risks as compared to myomectomy and hysterectomy. MRgFUS can be offered to a majority of patients suffering from sym...

Fibroids are the commonest uterine neoplasms, occurring in 20% - 30% of women of reproductive age. In women who have pelvic masses of unknown cause, unusual manifestations of fibroids such as necrosis or degeneration may simulate a carcinoma or hydrometra resulting in problems with image interpretation. We report a case of an unsuspected large degenerated uterine fibroid in a lady mistakenly di...

BACKGROUND Intramural leiomyomas have been long debated as a potential cause of infertility and pregnancy loss. FINDINGS Previous research has linked intramural fibroids to defective implantation, as well as to abnormal peristaltic events of the uterine smooth muscle. Previous reports describe the effects of intramural fibroids on normal human fertility and early pregnancy loss, specifically ...

Background: Focused ultrasound surgery (FUS) is a novel noninvasive surgery that results in localized tissue necrosis without any breech of the skin or other body orifice. MRI guidance provides anatomic visualization and real time thermal feedback. Our goal is to safely extend this therapy to women who desire future pregnancies. Materials and Methods: We have undertaken 4 multisite trials of FU...

Smptomatic uterine fibroids are estimated to occur in 25-50% of women of reproductive age, causing severe menstrual cramps, menorrhagia (which can result in anemia), reduced fertility, and/or symptoms of pressure, such as urinary frequency, a feeling of heaviness or bloating, or pain due to nerve compression. There are several treatment options for symptomatic fibroids, including myomectomy, hy...