Leukocyte migration from the blood into tissues is pivotal in immune homeostasis and in inflammation. During the multistep extravasation cascade, endothelial selectins (Pand E-selectin) and vascular adhesion protein-1 (VAP-1), a cell-surface– expressed oxidase, are important in tethering and rolling. Here, we studied the signaling functions of the catalytic activity of VAP-1. Using human endoth...

We present an inflationary universe model which utilizes two coupled real scalar fields. The inflation field φ experiences a first order phase transition and its potential dominates the energy density of the Universe during the inflationary epoch. This field φ is initially trapped in its metastable minimum and must tunnel through a potential barrier to reach the true vacuum. The second auxiliar...

sandwich sheet rolling process is investigated using an analytical method (slab method) and a numerical method (finite element method). the horizontal stress distribution in the layers, the rolling pressure along the contact interface and the neutral point between the roll and the sheet are investigated. then the affects of the parameters such as the friction between the sheet and the roll, she...

Leukocyte migration from the blood into tissues is pivotal in immune homeostasis and in inflammation. During the multistep extravasation cascade, endothelial selectins (P- and E-selectin) and vascular adhesion protein-1 (VAP-1), a cell-surface-expressed oxidase, are important in tethering and rolling. Here, we studied the signaling functions of the catalytic activity of VAP-1. Using human endot...

This paper proposes a novel and mechanically decoupled leg and wheel hybrid transformable robot called HyTRo-I that combines two mobility concepts. For example, while wheeled vehicles shares higher speed than legged and tracked machines on a flat ground, they have relatively lower degree of flexibility than the other two on irregular terrain. The HyTRo-I robot evolves three motion modes: wheele...

Isothermal interrupted hot compression tests of 5754 aluminum were conducted on a Gleeble-3500 thermo-mechanical simulator at temperatures of 350 °C and 450 °C, and strain rates of 0.1 s−1 and 1 s−1. To investigate the metadynamic recrystallization behavior, a range of inter-pass delay times (5–60 s) was employed. These tests simulated flat rolling to investigate how softening behaviors respond...

The rolling process is an excellent method for processing new high performance polymers. Skew rolling, as a highly accurate and highly efficient rolling technology, has been commonly used to enhance mechanical properties and productivity. However, the complexity of the mechanics in the skew rolling process of polymers is a significant challenge for manufacturers and researchers. In this work, m...

Surface elevation is a critical data for geo-science study. As far as some regions with rapidly-changing in landform, analyzing the surface elevation of different periods help provide scientific basis for regional economic & social sustained development. Jiangsu coast is force tide zone, and the complicated sediment dynamical environment, gently rolling tidal-flat landform, huge spatial differe...