We tested the hypothesis that thermal tail-flick latency, a common measure of pain sensitivity in rodents, would be altered in lines of mice that had been selectively bred for high voluntary wheel-running behavior. Specifically, we predicted that the selected (High-Runner) lines would show decreased pain sensitivity relative to their control (C; randombred) lines, and would respond differently ...

Substantial evidence has accumulated that spinally projecting serotonergic neurons modulate nociception. However, the exact receptor subtypes that mediate the antinociceptive response of serotonin within the spinal cord continue to be a subject of debate. Therefore, we explored the effect of serotonergic system on imipramine induced antinociception by using 5-Hydroxytryptamine-3 (5HT3) receptor...

in traditional medicine,some plants have been used as analysics.the aim of this investigation was to evaluate the analgesic effect of two plants,piper nigrum and Zingiber officinale that are used  traditionally to relieve headache,rheumatic arthritis,and toothache.for this purpose the methanolic extract of zingiber and piper nigrum,in different doses,were injected intraperitonealy to mice and t...

Most studies of lobster chemoreception have focused on the model systems of Panulirus argus (Palinuridae) and Homarus americanus (Nephropidae). We compare antennule morphology across lobsters and conduct the first kinematic study of antennule flicking in a palinurid species other than P. argus. High-speed video analysis shows that Palinurus elephas flicks at a rate more than an order of magnitu...

  Bibliographical studies have been done on plants that are used as analgesics in traditional medicine, and Mellissa officinalis or Lemon Balm (LB) that there are some evidence indicating for its application as analgesics or its probable analgesic effect was selected for evaluation of analgesic effect by tail-flick test in mice. After scientific identification, the leaves and flowered branches ...

Evaluation of Flick and Ring Scrolling on TouchBased Smartphones Huawei Tu, Xiangshi Ren, Feng Tian & Feng Wang To cite this article: Huawei Tu, Xiangshi Ren, Feng Tian & Feng Wang (2014) Evaluation of Flick and Ring Scrolling on Touch-Based Smartphones, International Journal of Human-Computer Interaction, 30:8, 643-653, DOI: 10.1080/10447318.2014.907017 To link to this article: http://dx.doi.o...

Administration of ethanol (95%) extract (45 mg/kg body wt/day for 28 days) of garlic (A. sativum) to alloxan induced diabetic (ALX-D) mice significantly lowered the serum glucose levels, nociceptive response in tail-flick, hotplate, allodynia, formalin test and relative thickness, weight of hind paw in formalin induced Paw oedema test, over 28 days, thus, showing the reversal trend in hyperglyc...

Microsaccades are miniature eye movements produced involuntarily during visual fixation of stationary objects. Since their first description more than 40 years ago, the role of microsaccades in vision has been controversial. In this issue, Martinez-Conde and colleagues present a solution to the long-standing research problem connecting this basic oculomotor function to visual perception, by sho...

Environmental noise is a known stress, which induces alterations of various physiological responses in individuals exposed to it. Stress has been shown to cause changes in the perception of various sensations including pain and stress-induced analgesia has been observed following exposure to a diverse set of stimuli. To examine the algesic behavior of rats exposed to loud environmental noise, f...