In an era of ever-increasing antibiotic resistance, antimicrobial stewardship plays a vital role in improving patient outcomes and ensuring the appropriate use of these agents. In this issue of Clinical Infectious Diseases, Hamilton et al acknowledge that most formalized antimicrobial stewardship programs (ASPs) do not currently employ a routine intervention with the antibiotic prescriber at th...

methyl tertiary butyl ether (mtbe) is known as a promising substitute for tetra ethyl lead (tel) in order to increase the octane number of gasoline. mtbe process, as many other processes, has two distinguished section, namely reaction section and separation section. in this paper we focus only on synthesis and optimization of separation section of this process. in order to achieve this objectiv...

Abstract Automated flowsheet synthesis is an important field in computer-aided process engineering. The present work demonstrates how reinforcement learning can be used for automated without any heuristics or prior knowledge of conceptual design. environment consists a steady-state simulator that contains all physical knowledge. An agent trained to take discrete actions and sequentially build u...

The development of reliable and fast automated methodologies to detect identify radionuclides during the decommissioning nuclear power plants is paramount importance. In this regard, process flowsheeting computational simulations are useful tools aid design testing these advanced detection technologies. We implement an optimization based procedure for continuous analysis systems on microfluidic...

This study is the first to provide a systematic approach assessing potential of advanced reactive distillation technologies expand applicability distillation. The work presented here focuses on synthesis technologies, proposing conceptually based methodology for early-stage screening. uses basic thermodynamic and kinetic data navigate decision-making flowchart in four steps: compositions splits...