Hepatic lesions are frequently identified incidentally on • imaging performed for other purposes. With the exception of large lesions, benign hepatic neo• plasms are typically asymptomatic. With current high quality imaging, it is possible to differentiate • the majority of hepatic neoplasms as benign or malignant. Resection of indeterminant, worrisome lesions is generally • preferred over biop...

BACKGROUND The role of tumour inflammation and the dysplastic epithelial-stromal interactions on the nature of collagen fibres in the extracellular matrix of dysplastic epithelium is not fully understood. The present study was aimed to evaluate and compare the inflammation and pathological stromal collagen (loosely packed thin disorganized collagen) present in mild, moderate and severe epitheli...

Background: Focal nodular hyperplasia (FNH) of the liver is a benign hepatic lesion relatively common in women. No studies specifically designed to describe the presentation and imaging findings in males have been published. Aims: The aims of this study were: (a) to describe the clinical and imaging findings in 18 men with FNH, and (b) to compare these data with those observed in 216 women with...

The aim of the study is to evaluate the contrast enhanced power doppler technique as a method to detect and differentiate vascular patterns of focal liver lesions. Fourty-nine patients with focal liver lesions were included in the study, twenty-nine of them with malignant liver lesions (9 HCC, 20 metastatic), twenty patients with benign lesions (12 haemangiomas, 5 focal nodular hyperplasia, 3 f...

keratoacanthoma (ka) is a comparatively common low-grade tumor that initiates in the pilo-sebaceous glands and pathologically mimics  squamous cell carcinoma (scc). essentially, strong debates confirm classifying keratoacanthoma as a variant of invasive scc. the clinical behavior of ka is hardly predictable and the differential diagnosis of keratoacanthoma and other conditions with keratoacanth...

Pseudoepitheliomatous hyperplasia is a benign reactivated epithelial lesion secondary to another pathology, whose incidence is difficult to establish. There still exist controversies regarding the origin and pathogenesis of these lesions. For this purpose, we performed an immuno-histochemical study upon 20 cases of oral pseudoepitheliomatous hyperplasia associated with inflammatory and neoplast...