نتایج جستجو برای: fold combinations
تعداد نتایج: 219280 فیلتر نتایج به سال:
Abstract Recurrent glioblastoma (GBM) is an aggressive disease with poor survival and limited treatment options. SL-701 a novel immunotherapy comprised of synthetic peptides designed to elicit anti-tumor immune response against GBM antigens IL-13Rα2, ephrinA2, survivin. Here we describe 18-color flow cytometry analysis from stage 2 Ph2 clinical trial SL-701+poly-ICLC+bevacizumab (NCT02078648), ...
Micelles are the simplest example of self-assembly found in nature. As many other colloids, they can self-assemble in aqueous solution to form ordered periodic structures. These structures so far all exhibited classical crystallographic symmetries. Here we report that micelles in solution can self-assemble into quasicrystalline phases. We observe phases with 12-fold and 18-fold diffraction symm...
Operads were originally defined as V-operads, that is, enriched in a symmetric or braided monoidal category V. The symmetry or braiding in V is required in order to describe the associativity axiom the operads must obey, as well as the associativity that must be a property of the action of an operad on any of its algebras. A sequence of categorical types that filter the category of monoidal cat...
Abstract Combinatorial CRISPR-Cas screens have advanced the mapping of genetic interactions, but their experimental scale limits number targetable gene combinations. Here, we describe 3Cs multiplexing, a rapid and scalable method to generate highly diverse uniformly distributed combinatorial CRISPR libraries. We demonstrate that library distribution skew is critical determinant its required scr...
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