It has been shown in a preceding paper (5) that thirteen agents known to have an anti-tumor effect in animals or man were highly cytotoxic against a number of cultured human and animal cells, inhibiting growth at concentrations of 10~5 to 10~9 M. Conversely, two folie acid analogs which were essentially devoid of anti-tumor action in vivo were relatively inactive in cell cultures. These finding...

cet article est consacréà l’étude du dialogue dans enfance, récit autobiographique de nathalie sarraute qui contient des souvenirs de ses onze premières années. l’une des originalités de ce récit, se base sur la présence de deux voix narratives qui dialoguent tout au long du récit. l’une de ces dernières, joue le rôle d’une narratrice et l’autre représente le côté conscient de l’auteur qui suiv...

SUMMARY A 50-year-old factory worker was admitted to hospital following an altercation with fellow workers. He reported a 25-year history of grandiose delusions related to being a special agent for the Taiwanese and US governments (for which he had been paid 100 million dollars) and paranoid delusions related to persecution by China's national security agencies. After detailed assessment by sev...

units for the synthesis of the purine ring and the methylation of uridylate to thymidylate is a fundamental requirement for cell replication. The mammalian cell cannot synthesize the basic pteroylglutamate structure and, consequently, growth and maturation of both normal and neoplastic cells require an exogenous source of this vitamin. For this reason, the folate coenzymes have been the target ...

2 cases of laurence- moon-biedl syndrome are described in 2 rothers. they have 5 out of 6 cardinal symptoms of this syndrome i.e. : i) obesity ,2) genital dystrophia, 3) retinitis pigmentosa, 4)menal deficiency, 5) familial occurrence. besides, their only sister has ocular signs of beginning of retinitis igmentosa and one of their relatives had polydactylism and another ne cretinism. what is cu...

Les écrits des juristes et administrateurs coloniaux français de la première moitié du xxe siècle sont ponctués d’expressions telles que « mentalité indigène », primitive âme ou encore esprit ». Évoquant un univers mental autre, ces formulations utilisées pour légitimer le recours à droit spécial, adapté au niveau développement psychique populations colonisées. Que se passe-t-il lorsque l’altér...