Nanoemulsions have been widely applied to dermal and transdermal drug delivery. However, whether and to what depth the integral nanoemulsions can permeate into the skin is not fully understood. In this study, an environment-responsive dye, P4, was loaded into nanoemulsions to track the transdermal translocation of the nanocarriers, while coumarin-6 was embedded to represent the cargoes. Particl...

STUDY QUESTION Are urinary phthalate metabolites associated with reduced antral follicle growth among women in an infertility setting? SUMMARY ANSWER Higher urinary concentrations of di(2-ethylhexyl) phthalate (DEHP) metabolites were associated with significant decreases in antral follicle count (AFC) among women seeking infertility care. WHAT IS KNOWN ALREADY Experimental animal studies sh...

The objective of the present study was to detect polymorphism in follicle stimulating hormone receptor (FSHR) and beta subunit of follicle stimulating hormone (FSHβ) genes and their relation to litter size and body weight trait in Baluchi, Iran black and Arman sheep breeds. PCR-RFLP technique using ACCI and HinfI enzyme treatments employed to detection of polymorphism in FSHβ marker site but de...

the objective of the present study was to detect polymorphism in follicle stimulating hormone receptor (fshr) and beta subunit of follicle stimulating hormone (fshβ) genes and their relation to litter size and body weight trait in baluchi, iran black and arman sheep breeds. pcr-rflp technique using acci and hinfi enzyme treatments employed to detection of polymorphism in fshβ marker site but de...

Objective: The level of dental and oral hygiene on elementary school age children is very low, so it can be increasing the incidence of dental and oral diseases which caused by various microorganisms. Mouthwash can keeping dental and oral hygiene, but many commercial mouthwash is still used alcohol as their ingredients, which can be giving side effects, therefore, we still need...

Objective: The level of dental and oral hygiene on elementary school age children is very low, so it can be increasing the incidence of dental and oral diseases which caused by various microorganisms. Mouthwash can keeping dental and oral hygiene, but many commercial mouthwash is still used alcohol as their ingredients, which can be giving side effects, therefore, we still need...

Anti-Mllerian hormone (AMH) is a product of growing ovarian follicles. Its concentration in blood may also reflect the non-growing follicle (NGF) pool (the ovarian reserve) and the rate of activation of follicle growth, and be of value in determining likely age at menopause. We have established AMH concentrations in women from age -0.3 to 59 years, using published data from normal women (n=1099...

An experiment was conducted to ascertain if follicles could reach ovulatory size after the largest follicle (dominant) has been removed at different times during a progestin treatment in anestrous ewes, and secondly to determine if these new follicles could respond to an hCG-induced ovulation and have similar function as corpora lutea. Mature crossbred sheep (n=44) in anestrous were treated wit...

Follicle development is accompanied by proliferation of granulosa cells and increasing oocyte size. To obtain high-quality oocytes in vitro, it is important to understand the processes that occur in oocytes and granulosa cells during follicle development and the differences between in vivo and in vitro follicle development. In the present study, oocytes and granulosa cells were collected from e...