The aims of this study were to characterize the presence of apathy in patients with AD, determine the relationship between apathy, motor function and cognitive function, and to verify differences among patients stratified by level of apathy in relation to cognitive and motor abilities. Methods A cross-sectional study was conducted of 37 patients with AD. The following tests were used: MoCA, t...

background morphometric data of the frontal lobe are important for surgical planning of lesions in the frontal lobe and its surroundings. magnetic resonance imaging (mri) techniques provide suitable data for this purpose. objectives in our study, the morphometric data of mid-sagittal mri of the frontal lobe in certain age and gender groups of children have been presented. patients and methods i...

Deficit schizophrenia is a relatively homogeneous subtype of patients which is considered helpful to explore the pathogenesis of schizophrenia. The aim of the present study was to reexamine the clinical characteristics of deficit (n=30) and nondeficit schizophrenia (n=93) in a Chinese sample and investigate the differences of neurocognitive function among the two subtypes of schizophrenia and t...

OBJECTIVE To elaborate a brief but efficient neuropsychological assessment of frontotemporal dementia (FTD), selecting the most specific and sensitive cognitive and behavioural items for distinguish between AD and FTD in the earlier dementia stages. METHODS Retrospective study with three groups, 35 patients with FTD, 46 with AD and 36 normal subjects, were administered the MMSE, FAB, Tower of...

Hypofrontality is a state of decreased cerebral blood flow in the prefrontal cortex during executive function performance; it is commonly observed in patients with schizophrenia. Cognitive dysfunction, as well as the psychological symptoms of schizophrenia, influences the ability of patients to reintegrate into society. The current study investigated the effects of an interactive sports video g...

The field of neuropsychology has made significant gains regarding the development and implementation of diagnostic measures and assessment techniques for frontal lobe pathology. Nevertheless, it is becoming increasingly evident that the existing battery of tests remains relatively insensitive to the ever-growing range of functions known to be mediated by the prefrontal regions. In the present s...

BACKGROUND The spectrum of abnormal behaviors in amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) has been described, but its practical meaning, namely its impact on caregiver burden, has not been clearly documented in Chinese population. This study aimed to assess the distribution of abnormal behaviors in Chinese population, and to analyze the relationship between behavior changes ...

Objectives: To assess efficacy of L-dopa treatment on aggression, frontal lobe and task switching deficits in patients with Parkinson’s disease (PD).
 Study Design: Prospective comparative study.
 Place Duration Study: Bahawal Victoria Hospital Civil Bahawalpur, Pakistan, from Apr 2016 to Oct 2017.
 Methodology: Seventy-five healthy individuals seventy-five PD participated the st...

Background. The growing number of patients with dementia in aging population developed countries significantly increases the relevance differential diagnosis cognitive impairment and age-associated disorders. purpose study was to determine criteria for physiological changes status diffusion processes brain’s white matter healthy middle-aged elderly people. Material ­methods. Thirty-nine (45–59 ...