INTRODUCTION Major Depressive Disorder (MDD) is a leading cause of disease burden worldwide. Mood-congruent biases in memory tasks are frequently reported in MDD patients, with facilitated memory for negative stimuli. Most functional MRI studies to date have examined the neural correlates of these biases in depressed adults, with fewer studies in adolescents with MDD. Investigation of MDD in ad...

OBJECTIVE The goal of this study was to determine prevalence and odds of functional disability in individuals with diabetes and comorbid major depression compared with individuals with either diabetes or major depression alone. RESEARCH DESIGN AND METHODS Data on 30,022 adults aged > or = 18 years from the 1999 National Health Interview Survey (NHIS) were analyzed. Four disease categories wer...

OBJECTIVE To examine if self-reported number of teeth, denture use and chewing ability are associated with incident falls. DESIGN Longitudinal cohort study (the Aichi Gerontological Evaluation Study). SETTING 5 Japanese municipalities. PARTICIPANTS 1763 community-dwelling individuals aged 65 years and older without experience of falls within the previous year at baseline. MAIN OUTCOME M...

OBJECTIVE Functional magnetic resonance imaging (MRI) was used to investigate the hypothesis that attention deficit hyperactivity disorder (ADHD) is associated with a dysfunction of prefrontal brain regions during motor response inhibition and motor timing. METHOD Generic brain activation of seven adolescent boys with ADHD was compared to that of nine comparison subjects equivalent in sex, ag...

In the 1980s and 1990s, there was a major theoretical debate in the memory domain regarding the multiple memory systems and processing modes frameworks. The components of processing framework argued for a middle ground: Instead of neatly divided memory systems or processing modes, this framework proposed the existence of numerous processing components that are recruited in different combination...

Fear of falling (FOF) is expected to have effects on functional decline in the elderly. In this study, we examined over 2 years the effect of change in FOF on functional decline in community dwelling elderly. We conducted a secondary analysis using data from elderly women, 70 years of age and older, who participated in the Korean Longitudinal Study of Aging (KLoSA). Participants were divided in...

The purpose of the article was to provide an overview of patient-reported outcomes (PROs) and related measures that have been examined in the context of obsessive-compulsive disorder (OCD). The current review focused on patient-reported outcome measures (PROMs) that evaluated three broad outcome domains: functioning, health-related quality of life (HRQoL), and OCD-related symptoms. The present ...