Superparamagnetic iron oxide nanoparticles (SPION), as magnetic resonance (MR) imaging contrast agents or magnetic targeting carriers, have potential applications in diagnostics, imaging, cell and drug/ gene delivery for cardiovascular diseases. SPION are highly magnetic particles that cause magnetic field perturbations, which can be identified on T2* weighted images [1]. Clinically, SPION allo...

Introduction: Iron plays an important role in physiological processes as a trace element. Today, iron oxide nanoparticles have attracted extensive attention due to their super paramagnetic properties and a variety of potential applications in many fields. The main objective of this study was to evaluate in vitro and in vivo toxic effects of the iron oxide nanoparticles on L929 cell line, kidney...

Present work describes the formation of α-Fe2O3@SiO2 core shell structure by systematic layer by layer deposition of silica shell on core iron oxide nanoparticles prepared via various solvents. Sol-gel method has been used to synthesize magnetic core and the dielectric shell. The average crystallite size of iron oxide nanoparticles was calculated ∼20 nm by X-ray diffraction pattern. Morphologic...

Over loading of iron oxide nanoparticles can causes the liver injury through overproduction of free radicals. Zataria multiflora Boiss. (Lamiaceae) has been used for many years in folk medicine due to its antioxidant and antibacterial activities. This study evaluates -for the first time- the effect of Z. multiflora essential oil (EO) against iron oxide nanoparticles hepatotoxicity in rat model....

In recent years much attention has been paid to the synthesis of metal and metal oxide nanoparticles with tailored size and morphology, and to appropriate functionalization in their periphery [1]. In addition to several types of polymers, long-chain organic molecules play an important role as ligands for nanoparticles to prevent their agglomeration and to provide the necessary functionalization...

Iron oxide nanoparticles have been explored recently for their beneficial applications in many biomedical areas, in environmental remediation, and in various industrial applications. However, potential risks have also been identified with the release of nanoparticles into the environment. To study the ecological effects of iron oxide nanoparticles on aquatic organisms, we used early life stages...

PURPOSE The presence of tumor-associated macrophages (TAM) in breast cancer correlates strongly with poor outcome. The purpose of this study was to develop a clinically applicable, noninvasive diagnostic assay for selective targeting and visualization of TAMs in breast cancer, based on magnetic resonanceI and clinically applicable iron oxide nanoparticles. EXPERIMENTAL DESIGN F4/80-negative m...

Electrocatalysis of oxygen reduction using Pt nanoparticles supported on functionalized graphene sheets (FGSs) was studied. FGSs were prepared by thermal expansion of graphite oxide. Pt nanoparticles with average diameter of 2 nm were uniformly loaded on FGSs by impregnation methods. Pt-FGS showed a higher electrochemical surface area and oxygen reduction activity with improved stability as com...

objective: the label and detection of cells injected into target tissues is an area of focus for researchers. iron oxide nanoparticles can be used to label cells as they have special characteristics. the purpose of this study is to examine the effects of iron oxide nanoparticles on human-derived amniotic membrane stem cell (hamcs) survival and to investigate the magnetic properties of these nan...

several mri contrast agents (cas) are used in medical diagnosis that gadolinium (gd3+) is the most widely used as contrast agents. unfortunately, its toxicity is due to its inefficiency. in this review, we discuss about the ability of spions in mri and application in multiple sclerosis diagnosis. superparamagnetic iron oxide nanoparticles (spions) such as magnetite nanoparticles are used as goo...