Monodisperse butylphenyl-functionalized palladium (Pd-BP, dia. 2.24 nm) nanoparticles were synthesized through co-reduction of butylphenyldiazonium and H(2)PdCl(4) by NaBH(4). Because of this unique surface functionalization and a high specific electrochemical surface area (122 m(2) g(-1)), the Pd-BP nanoparticles exhibited a mass activity ∼4.5 times that of commercial Pd black for HCOOH electr...

Zeolite nanoparticles with various organosilanized surfaces have been synthesized in situ by a one-step approach which provides not only a functionalized surface for diverse host-guest interactions but also an attractive path for preparation of monodispersed template-free zeolite nanoparticles.

Effective and specific targeting of nanoparticles is of paramount importance in the fields of targeted therapeutics and diagnostics. In the current study, we investigated the targeting efficacy of nanoparticles that were functionalized with two angiogenesis-specific targeting ligands, an alpha(v)beta(3) integrin-specific and a galectin-1-specific peptide. We show in vitro, using optical techniq...

A one-dimensional assembly of cadmium sulfide (CdS) nanoparticles was prepared by using functionalized polymers with pendant Fréchet-type dendritic wedges of different generation. The novel dendronized polymers acted as both nanoreactors for the formation of CdS nanoparticles and a template to arrange the nanoparticles into a necklace. The polymers of different dendron generation were applied t...

Molecular detection of target molecules with high sensitivity and specificity is of great significance in bio and medical sciences. Here, we present genetically functionalized ferritin nanoparticles with a high-affinity protein binder, and their utility as a signal generator in a variety of immunoassays and imaging. As a high-affinity protein binder, human IgG-specific repebody, which is compos...

BACKGROUND Nanoparticles have a large number of surface atoms, which translates into a significant increase in the surface energy. Once introduced in a biological environment they tend to interact with proteins and form a protein corona shell. The aim of this study was to develop a novel, silver based, bio-nanocomposite for biological applications. Immunoglobulin G (IgG) molecule was chosen for...

Photodynamic therapy (PDT) is an emerging theranostic modality for various cancer as well as non-cancer diseases. Its efficiency is mainly based on a selective accumulation of PDT and imaging agents in tumor tissue. The vascular effect is widely accepted to play a major role in tumor eradication by PDT. To promote this vascular effect, we previously demonstrated the interest of using an active-...

In this article, a systematic study of the design and development of surface-modification schemes for silica nanoparticles is presented. The nanoparticle surface design involves an optimum balance of the use of inert and active surface functional groups to achieve minimal nanoparticle aggregation and reduce nanoparticle nonspecific binding. Silica nanoparticles were prepared in a water-in-oil m...

Biofunctionalized gold and silver nanoparticles synthesized using different plant extracts of guava and clove in vitro anti-cancer efficacy against four different cancer cell lines human colorectal adenocarcinoma, human kidney, human chronic myelogenous, leukemia, bone marrow, and human cervix have been studied and reported. The present experimental study suggests that flavonoids functionalized...

Low Curie temperature NiPd seeds have been studied as potential materials for self-regulated hyperthermia. The invasive deposition of these seeds can be overcome by the use of NiPd nanoparticles with functionalized surfaces. The present work discusses two new methods of preparation of NiPd nanoparticles. The particles have been characterized by x-ray diffraction, energy dispersive spectrometry,...