Gamma-aminobutyric acid (GABA) metabolism was studied in rats chronically exposed to 2.86 GHz microwaves at an incident power level of 10 mW/cm or acutely exposed to incident power levels of 40 or 80 mW/cm. No changes occurred in whole brain GABA levels or L-glutamic decarboxylase activity following these exposures. These results suggest that an altered GABA metabolism is not involved in report...

................................................................................................87 Autobiographical Statement...................................................................89

Gamma-hydroxybutyric acid (GHB) is a short-chain fatty acid structurally similar to the inhibitory neurotransmitter gamma-aminobutyric acid. Clinical trials have demonstrated that 50-100 mg/kg of GHB fractioned into three or six daily doses is able to suppress alcohol withdrawal symptoms and facilitates the maintenance of abstinence from alcohol. These studies have also shown that GHB craving e...

State Key Laboratory of Microbial Resources and Dept. of Industrial 4 Microbiology and Biotechnology, Institute of Microbiology, Chinese Academy of 5 Sciences, Beijing 100101, PR China; Key Laboratory of Agricultural and 6 Environmental Microbiology, Wuhan Institute of Virology, Chinese Academy of 7 Sciences, Wuhan 430071, People's Republic of China 8 9 Running title 10 GABA uptake system in C....

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