Singh VK, Singh DK. Pharmacological Effects of Garlic (Allium sativum L.). ARBS Annu Rev Biomed Sci 2008;10:6-26. Garlic (Allium sativum L.) is a bulbous herb used as a food item, spice and medicine in different parts of the world. Its medicinal use is based on traditional experience passed from generation to generation. Researchers from various disciplines are now directing their efforts towar...

We investigated the effect of garlic oil (GO), alone or combined with low dose total body gamma (γ)-irradiation (LDR) against paracetamol (APAP)induced hepatotoxicity in rats. GO (100 mg/kg/day) was administered orally for 14 days before hepatotoxicity induction.Animals were irradiated 2 hours before hepatotoxicity induction by peroral APAP (1g/kg) administration, then animals were sacrificed 2...

Precursors involved in the formation of pink and green-blue pigments generated during onion and garlic processing, respectively, have been studied. It has been confirmed that the formations of both pigments are of very similar natures, with (E)-S-(1-propenyl)cysteine sulfoxide (isoalliin) serving as the primary precursor. Upon disruption of the tissue, isoalliin and other S-alk(en)ylcysteine su...

The effects of commercial thyme, sage, garlic, sesame, rosemary, lemon and mustard essential oils (Botalife Natural Aromatic Products Ltd. Şti, Turkey) on disease severity were investigated in simultaneous inoculation Meloidogyne incognita (Kofoid White, 1919) Chitwood, 1949 Fusarium oxysporum f.sp.radicis lycopersici (Jarvis & Shoemaker) tomato. Nematicide (Velum®, Fluopyram) fungicide (Ce...

The immunomodulatory proteins present in garlic have recently been shown to be identical to the garlic lectins ASA I and ASA II [Clement F, Pramod SN, Venkatesh YP. Int. Immunopharmacol. 2010; 10: 316-324]. In this study, the stability of garlic lectins as a function of pH, temperature and denaturants has been examined in relation to biological activity (hemagglutination and hagocytosis). Stabi...

Semen oxidation is one of the major testimonies of infertility. The aim of present study was to examine the effects of fresh garlic juice on semen malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPx) and total antioxidant status (TAS) compared with chromium chloride (CrCl3) in male rats. A hundred and sixty-two male rats were allocated into 9 treatment groups. Group 1...

An experiment was conducted to assess the effect of dietary supplementation of garlic (Allium sativum) and fenugreek (Trigonella foenum-graecum L.) seed powder as herbal feed additives on growth performance, carcass characteristics and economics of feeding in broilers. A total of 320 day old broiler chicks of Cobb-400 strain were divided into four treatment groups with 4 replicates of 20 chicks...

Louis Pasteur was the first to describe the antibacterial effect of onion and garlic juices. Historically, garlic has been used worldwide to fight bacterial infections. Allium vegetables, particularly garlic (Allium sativum L.) exhibit a broad antibiotic spectrum against both gram-positive and gram-negative bacteria. Noteworthy results published include the following: 1) raw juice of garlic was...

Garlic and its preparations have been widely recognized as agents for prevention and treatment of cardiovascular and other metabolic diseases, atherosclerosis, hyperlipidemia, thrombosis, hypertension and diabetes. Effectiveness of garlic in cardiovascular diseases was more encouraging in experimental studies, which prompted several clinical trials. Though many clinical trials showed a positive...