Concepts of the spectrum of gastroesophageal reflux disease (GERD) continue to evolve as researchers and clinicians challenge conceptual frameworks and explore new paradigms aided by innovative technologies and novel developments in symptom assessment. In this review, the deliberations of a meeting of experts in gastroenterology (Athens, 2006) are presented as a critical evaluation of the curre...

introduction: laryngopharyngeal reflux (lpr) is considered an important cause of voice disorder. we aimed to determine the frequency of lpr in patients with voice disorder and the association between koufman reflux symptom index (rsi), reflux finding score (rfs), gastroesophageal reflux disease (gerd), and proximal acid reflux in these patients. materials and methods: we performed a prospective...

BACKGROUND/AIMS Different non-invasive diagnostics strategies have been used to assess patients with gastroesophageal reflux. Gastroesophageal reflux disease (GERD) questionnaire (GerdQ) is a 6-item, easy to use questionnaire that was developed primarily as a diagnostic tool for GERD in primary care. Our aim was to validate and assess diagnostic utility of GerdQ questionnaire in Mexican patient...

Gastroesophageal reflux disorder (GERD), a common disorder in the Western world, can lead to complications that include esophageal stricture and esophageal adenocarcinoma. Multiple challenges are associated with GERD treatment. First, lack of symptoms does not correlate with the absence of or the healing of esophageal lesions. Second, proton pump inhibitors, the current standard of care for GER...

The research pays more attention on evaluating the impact of patient education as directed by a clinical pharmacist concerning disease, useful effects treatment, causes life style modifications and finally improving quality patients diagnosed with Gastroesophageal reflux disease (GERD). It is prospective observational study, GSRS scores according to baseline, follow up1 up2 were 7.552 ± ...

OBJECTIVE To determine whether the presence of laryngopharyngeal reflux symptoms is associated with the presence of esophageal adenocarcinoma (EAC). BACKGROUND Most patients diagnosed with EAC have incurable disease at the time of detection. The majority of these patients are unaware of the presence of Barrett's esophagus prior to cancer diagnosis and many do not report typical symptoms of ga...

Cornelia de Lange syndrome (typus degenerativus amstelodamensis, CdLS, Brachmann syndrome) is a complex, congenital, multi-gene anomaly characterized by mental retardation. Its features include growth inhibition, hirsutism, structural anomalies of the limbs and abnormal development of osseous structures of the face. Independent of the phenotype of the disease, 85% of patients are assumed to hav...

BACKGROUND In traditional Chinese culture, liver disease is believed to underlie excessive daytime sleepiness (EDS). Consequently, Chinese patients with complaints of EDS and physicians who treat them suspect that a liver abnormality is present. If liver disease is ruled out, these patients are often discharged without treatment. Gastroesophageal reflux disease (GERD) is a common disorder also ...

A 14-year-old male initially presented to the Emergency Department (ED) for a chronic, persistent cough and chest pain with concurrent history of asthma gastroesophageal reflux disease (GERD). He had been trialed on several medications before this visit cough, without resolution symptoms. Despite seeing specialists after ED being evaluated infectious causes other pulmonary issues, he was eventu...

Transoral incisionless fundoplication (TIF) has been used for endoscopic treatment of gastroesophageal reflux disease (GERD). TIF using the EsophyX device system (EndoGastric Solutions) was designed to create a full-thickness valve at the gastroesophageal junction through the insertion of multiple fasteners; it improves GERD, reduces proton pump inhibitor use, and improves quality of life. Alth...