نتایج جستجو برای: gastrointestinal stromal tumors gist

تعداد نتایج: 306212  

باقری, رضا, توسلی, علیرضا, مداح, قدرت الله, نقوی ریابی, فاطمه,

Background: Gastrointestinal mesenchymal tumors are classified as tumors that originate from smooth muscles. Gastrointestinal stromal tumors (GIST) are the most common types of the proposed tumors and can be seen in the GI tract from the esophagus to the anus, but they are mostly seen in the stomach. Mostly from the stomach and asymptomatic, the majority of patients would benefit from surgery a...

2017

Although their overall incidence is uncommon, gastrointestinal stromal tumors (GIST) are the most frequently encountered mesenchymal tumors of the GI tract. Their pathology has been recently defined by the presence of KIT (transmembrane receptor tyrosine kinase). The majority of GISTs have c-kit gain-of-function mutations mainly in exon 11 (highly conserved juxtamembrane region) that eventuates...

Journal: :Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2017
DănuŢ Vasile George Iancu Raluca Claudia Iancu George Simion Radu Constantin Ciuluvică

Duodenal gastrointestinal stromal tumors (GISTs) are uncommon. Tumors arising from the first and the second part of the duodenum (DI and DII, respectively) can be wrongly diagnosed as pancreatic mass. We present a case of a 59-year-old woman who came with abdominal pain and severe upper gastrointestinal bleeding (hemoglobin 3.5 g÷dL). A solid, heterogeneously enhancing neoplasm in the head of t...

Journal: :Cirugia y cirujanos 2009
Pablo Menéndez-Sánchez Pedro Villarejo-Campos Daniel Gambí-Pisonero Teófilo Cubo-Cintas David Padilla-Valverde Jesús Martín-Fernández

BACKGROUND Small bowel tumors comprise 25% of gastrointestinal (GI) neoplasms, of which only between 0.2 and 1% correspond to gastrointestinal stromal tumors (GIST). GI bleeding is the most common presentation of GIST, being responsible in 1% of the cases. This type of neoplasm can also be the origin of an intussusception, which is an infrequent process during adult age, representing only 5% of...

Journal: :Anticancer research 2012
Clara Rizzardi Stefania Marzinotto Claudio Avellini Mauro Melato Laura Mariuzzi

Gastrointestinal stromal tumors (GISTs) are the most common primary mesenchymal tumors of the gastrointestinal tract, and most of them harbor KIT or platelet-derived growth factor receptor alpha (PDGFRA) gain-of-function mutations. Proper diagnostic assessment of GISTs has become very important since the availability of the molecular-targeted therapy with imatinib mesylate. Histopathology remai...

2016
Minh Phan Shari Jones Justin Jenkins Shubham Pant Mohamad Khawandanah

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and usually occur in the stomach and the small intestine. The pancreas is an extremely rare primary site for GISTs and there are 25 reported cases of pancreatic GIST with most being treated with surgical resection. We describe a 52-year-old African-American female who was diagnosed with ...

Journal: :Oncology 2009
Margaret von Mehren James C Watson

Excellent safety, efficacy, and tolerability profiles have resulted in the rapid integration of oral tyrosine kinase inhibitors into most facets of the treatment of gastrointestinal stromal tumors (GIST). With these agents having firmly established themselves in the treatment of advanced unresectable disease, there is now a growing body of literature concerning their use in the perioperative se...

Journal: : 2023

The frequency of detection stromal gastrointestinal tumors in children and adolescents is about 0.4% the total number diagnosed GISTs. These can occur throughout tract. During instrumental research, misinterpretation tumor origin possible. For this reason, consistent use a variety non-invasive diagnostic methods extremely important preoperative period. We present case report rare GIST pediatric...

2013
Michele Danzi Luciano Grimaldi Massimiliano Fabozzi Umberto Robustelli Roberta Danzi Bruno Amato Stefano Reggio

Background Gastrointestinal stromal tumors (GISTs) constitute the most common non epithelial neoplasm that occur within the gastrointestinal tract with a world wide annual incidence of 8-14/million. They are usually located in the upper gastrointestinal tract particularly in the stomach (60%), in the small bowel (30%), esophagus (5%) and rectum (5%). Gist(s) origin from sporadic mutations withi...

Journal: :Journal of Medical Cases 2021

Gastrointestinal stromal tumors (GISTs) are non-epithelial that arise in the gastrointestinal tract. Pharmacological treatments for GIST tyrosine kinase inhibitors. For metastatic disease, debulking may be helpful reducing tumor burden, thus increasing effectiveness of Debate on whether resection would benefit patient is still present. Here a case 52-year-old African American male presenting wi...

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