Equitable global access to vaccines requires overcoming challenges associated with complex immunization schedules and their economic burdens that hinder delivery in under-resourced environments. The rabies vaccine, for example, multiple immunizations effective protection each dose is cost prohibitive, therefore inaccessibility disproportionately impacts low- middle-income countries. In this wor...

A number of ways have been investigated for administration of antibacterial agents in dealing of plaque-initiated periodontal disease. These include prolonged release intrapocket devices which are inserted at diseased sites. Intrapocket drug delivery system was designed which contain Doxycycline Hyclate an antibacterial agent. The formulations were so developed with an aim to reduce the dose of...

A number of ways have been investigated for administration of antibacterial agents in dealing of plaque-initiated periodontal disease. These include prolonged release intrapocket devices which are inserted at diseased sites. Intrapocket drug delivery system was designed which contain Doxycycline Hyclate an antibacterial agent. The formulations were so developed with an aim to reduce the dose of...

Accurate treatment planning in radiotherapy essentially decreases damage to healthy tissue surrounding the tumor. Due plans use a direct, highly collimated, narrow beam with high intensity treat small area tumors, researchers have studied microbeam radiation therapy extensively. Using synchrotron as source may help limit damage, but using computerized simulations and dosimetry is still necessar...

vesicoureteral reflux (vur) is a relatively common and important entity in children. vur can expose patient to risk of pyelonephritis, permanent renal damage or scar. vur itself has no deleterious effect on kidney parenchyma until the development of infection or increased intravesical pressure.   the diagnosis of vur could lead to appropriate therapy and prevention of long term complications. t...

The development of topical anti-human immunodeficiency virus (HIV) microbicides may provide women with strategies to protect themselves against sexual HIV transmission. Pericoital drug delivery systems intended for use immediately before sex, such as microbicide gels, must deliver high drug doses for maximal effectiveness. The goal of achieving a high antiretroviral dose is complicated by the n...

Gamma radiation triggered secondary crosslinking of dextran hydrogels leads to macroscopic hydrogel contraction. The authors use stable polymer hydrogels, prepared through azide-alkyne crosslinking, containing surplus alkyne groups. ?-irradiation these gels more enabling controlled increase crosslink density, which in turn an stiffness and Gel contraction scales linearly with the applied dose. ...