in the present study, mitochondrial dna polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) assay was used to assess the population structure and genetic relationships among six persian sturgeon, acipenser persicus populations from south caspian sea along the iranian coast. the complete nucleotide dehydrogenase subunit 5 (nadh 5) region of mtdna amplified by pcr was di...

Abstract. Wahidah, Omar SBA, Trijuno DD, Nugroho E, Amrullah, Khatimah K. 2023. Genetic variation of giant freshwater prawns Macrobrachium rosenbergii wild population South Sulawesi, Indonesia. Biodiversitas 24: 3081-3090. Quality prawn broodstock can be provided using sources from populations with good morphological and genetic performance. This study aimed to analyze the genotypes in hence it...

BACKGROUND Mutations in the solute carrier family 22 member 3 (SLC22A3), lipoprotein (a)-like 2 (LPAL2), and the lipoprotein (a) (LPA) gene cluster, which encodes apolipoprotein (a) [apo (a)] of the lipoprotein (a) [Lp (a)] lipoprotein particle, have been suggested to contribute to the risk of coronary artery disease (CAD), but the precise variants of this gene cluster have not yet been identif...

Evolutionary mechanisms have shaped the genomic architecture of Colombian Creole cattle breeds. The mating and selection processes impacted several traits, promoting differences within between populations. Studies population structure signatures in breeds are scarce, need more attention to better understand genetic differentiation, gene flow, distance. This study aimed analyze identify imprints...

Group 2 allergens (Der p2) have been reported to be a major cause of the human immune response to dust mite allergens. In this study, we have demonstrated for the first time the effective differentiation between haplotype mutation and normal genes in the MD-2 gene promoter using a nanostructured biosensor. A 70-mer gene fragment containing the haplotype of two single nucleotide polymorphisms in...

PSORS1 (psoriasis susceptibility gene 1) is a major susceptibility locus for psoriasis. Several fine-mapping studies have highlighted a 300-kb candidate region of PSORS1 where multiple biologically plausible candidate genes were suggested. The most recent study has indicated HLA-Cw6 as the primary PSORS1 risk allele within the candidate region in a Caucasian population. In this study, a family-...

The human angiotensinogen (hAGT) gene contains an A/G polymorphism at -217 and frequency of -217A allele is increased in African-American hypertensive patients. hAGT gene has seven polymorphic sites in 1.2Kb region of its promoter and variant -217A almost always occurs with -532T, -793A, and -1074T whereas variant -217G almost always occurs with -532C, -793G, and -1074G. Since allele -6A is the...

The human angiotensinogen (hAGT) gene contains an A/G polymorphism at -217, and frequency of -217A allele is increased in African-American hypertensive patients. The hAGT gene has seven polymorphic sites in the 1.2-kb region of its promoter, and variant -217A almost always occurs with -532T, -793A, and -1074T, whereas variant -217G almost always occurs with -532C, -793G, and -1074G. Since allel...

Both genetic and environmental interactions affect systemic lupus erythematosus (SLE) development and pathogenesis. One known genetic factor associated with lupus is a haplotype of the interferon regulatory factor 5 (IRF5) gene. Analysis of global gene expression microarray data using gene set enrichment analysis identified multiple interferon- and inflammation-related gene sets significantly o...

Little is known about the possible influence that past glacial events have had on the phylogeography and population structure of avian predators in the Arctic and sub-Arctic. In this study, we use microsatellite and mitochondrial control region DNA variation to investigate the population genetic structure of gyrfalcons (Falco rusticolus) throughout a large portion of their circumpolar distribut...