The aim of this research was to investigate the changes in milk yield and its composition, fatty acid profile and peroxisome proliferator-activated receptors gamma (PPARG) gene expression in adipose tissue of Iranian Holstein cattle in response to feeding isonitrogenous and isocaloric diets but formulated based on different oilseeds (soybean or canola seeds). Twenty cows were tested ra...

(SCNT) embryos of buffaloes. 2. To study gene expression profile of important developmental genes at different stages of SCNT cloned embryo. 3. To study epigenetic reprogramming during early developments of SCNT embryos Materials and Methods: Expression analysis of developmental genes was done in different (ovarian granulose and cumulus and skin fibroblasts) donor cells; in vitro maturing oocyt...

We propose a new method for identifying and validating drug targets by using gene networks, which are estimated from cDNA microarray gene expression profile data. We created novel gene disruption and drug response microarray gene expression profile data libraries for the purpose of drug target elucidation. We use two types of microarray gene expression profile data for estimating gene networks ...

Gene differential expression consists of the study possible association between gene expression, evaluated using different types data as DNA microarray or RNA-Seq technologies, and phenotype. This can be performed marginally for each (differential expression) a set collection (gene analysis). A previous (marginal) per-gene analysis is usually in order to obtain significant genes marginal p-valu...

Objective(s): The OCT4B1, as one of OCT4 variants, is expressed in cancer cell lines and tissues more than other variants and plays an important role in apoptosis and stress (heat shock protein) pathways. The present study was designed to determine the effects of OCT4B1 silencing on expressional profile of HSP40 gene family expression in three different human tumor cell lines. Materials and Met...

background and objective: recent studies have shown that not only the quantity, but also the quality of dietary fatty acids can affect lipid parameters. elaidic acid is a major hydrogenated by-product of vegetable oil play a role in the development of cardiovascular disease, especially atherosclerosis, through changing lipid profile and increase in inflammation and inflammatory factors. on the ...

Background: Psoriasis is a chronic inflammatory dermatosis. The hyperproliferation and hyperkeratosis of keratinocytes key step in the pathogenesis psoriasis. Long non-coding RNAs (lncRNAs) mRNAs regulate gene expression various biological process, including function keratinocytes. This research investigated profile lncRNAs patients with psoriasis vulgaris.