نتایج جستجو برای: genetic mapping
تعداد نتایج: 794475 فیلتر نتایج به سال:
The process of locating quantitative trait loci (QTLs) using genetic linkage maps, an ordered array of genetic markers placed along the chromosome, could be facilitated by applying e cient computer software packages. Construction of linkage maps requires that the rate of recombination be converted to distance in cM using appropriate mapping functions. However, computer software packages di er w...
Computing identity-by-descent sharing between individuals connected through a large, complex pedigree is a computationally demanding task that often cannot be done using exact methods. What I present here is a rapid computational method for estimating, in large complex pedigrees, the probability that pairs of alleles are IBD given the single-point genotype data at that marker for all individual...
A thorough examination of cotransformation of two unlinked genetic markers in Bacillus subtilis 168 shows that the two recombinational events do not occur randomly. The cotransformation frequency is dependent on the distance between the two markers as well as on the order in which they replicate in the competent cell. These results indicate that uptake and/or integration of DNA molecules bearin...
EARLIER genetic studies of Streptomyces cwlicolor utilized almost exclusively nutritional markers, and these identified two abundantly marked linkage groups (HOPWOOD 1965a). Later it was shown (HOPWOOD 1965b) that these linkage groups were segments of a circular map. The two intervening regions were very sparsely marked, and this accounted for the earlier finding of two independently segregatin...
Our understanding of the pathogenesis of endocrine disorders increase rapidly by genetic studies at the molecular level. Common endocrine disorders such as diabetes mellitus, obesity, osteoporosis, dyslipidemia and cancer follow the multifactorial model in the genetic aspect. This review tries to clarify the approach in molecular studies of such diseases for clinicians in different specialties....
Genetic mapping studies in the mouse and other model organisms are used to search for genes underlying complex phenotypes. Traditional genetic mapping studies that employ single-generation crosses have poor mapping resolution and limit discovery to loci that are polymorphic between the two parental strains. Multiparent outbreeding populations address these shortcomings by increasing the density...
Genetic mapping studies in the mouse and other model organisms are used to search for genes underlying complex phenotypes. Traditional genetic mapping studies that employ single-generation crosses have poor mapping resolution and limit discovery to loci that are polymorphic between the two parental strains. Multiparent outbreeding populations address these shortcomings by increasing the density...
Background Connecting phenotype with genotype is the basis for developing forest genetic applications such as marker assisted selection (MAS). Quantitative Trait Locus (QTL) mapping and genetic association mapping (or linkage disequilibrium (LD) are two major approaches to find genes that control phenotypes of interest in forest trees. Quantitative trait loci (QTL) and association mapping exper...
the present study sought to investigate the impact of using mind-mapping technique instruction on female elementary efl learners reading comprehension; it also investigated their attitudes towards using mind-mapping technique as a tool to improve their reading comprehension. this study followed a quasi-experimental design with two intact groups as experimental, and control groups. the participa...
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