Abstract Background The red panda ( Ailurus fulgens ) is a riddle of morphology, making it hard to tell whether an ursid, procyonid, mustelid, or member its own family. Previous genetic studies have given quite contradictory results as phylogenetic placement. Results A recently developed whole genome-based algorithm, the Whole Genome K-mer Signature algorithm was used analyze genomes 28 species...

Abstract 5-Hydroxymethylcytosine (5hmC) is an important epigenetic mark that regulates gene expression. Charting the landscape of 5hmC in human tissues fundamental to understanding its regulatory functions. Here, we systematically profiled whole-genome at single-base resolution for 19 types tissues. We found preferentially decorates bodies and outperforms body 5mC reflecting Approximately one-t...

Genome editing is a set of techniques for introducing targeted changes in genomes. It may be achieved by enzymes collectively called site-directed nucleases (SDN). Site-specificity SDNs provided either the DNA binding domain protein molecule itself or RNA molecule(s) that direct SDN to specific site genome. In contrast transgenesis resulting insertion exogenous DNA, genome only affects endogeno...

Gene duplication is the major resource with which to generate new genes, provide raw material for novel functions evolution. Thus, elucidate gene family evolution after events of vital importance. Anthocyanin O-methyltransferases (AOMTs) have been recognized as being capable anthocyanin methylation, increases diversity and stability improves protection plants from environmental stress. Meanwhil...

Abstract Background During the bread wheat speciation by polyploidization, a series of genome rearrangement and sequence recombination occurred. Simple repeat (SSR) sequences, predominately located in heterochromatic regions chromosomes, are effective marker for tracing genomic DNA variations. However, to date distribution dynamics SSRs on chromosomes its donors, including diploid tetraploid Tr...

Introduction Twenty years ago, the Human Genome Project made history by announcing sequencing of 92% human genome through development modern genetic techniques. In 2022, complete DNA was announced. This knowledge it possible to better understand how genetics influences functioning body and, at same time, facilitated identification variants that can cause diseases. field cardiology, study assist...