نتایج جستجو برای: genome analysis

تعداد نتایج: 2981438  

Journal: :Briefings in Bioinformatics 2017

Journal: :Current opinion in genetics & development 2012
Elaine R Mardis

New technologies for DNA sequencing, coupled with advanced analytical approaches, are now providing unprecedented speed and precision in decoding human genomes. This combination of technology and analysis, when applied to the study of cancer genomes, is revealing specific and novel information about the fundamental genetic mechanisms that underlie cancer's development and progression. This revi...

Background: Genome walking is a DNA-cloning methodology that is used to isolate unknown genomic regions adjacent to known sequences. However, the existing genome-walking methods have their own limitations. Objectives: Our aim was to provide a simple and efficient genome-walking technology. Material and Methods: In this paper, we dev...

2015
Gareth Highnam Jason J. Wang Dean Kusler Justin Zook Vinaya Vijayan Nir Leibovich David Mittelman

The standardization and performance testing of analysis tools is a prerequisite to widespread adoption of genome-wide sequencing, particularly in the clinic. However, performance testing is currently complicated by the paucity of standards and comparison metrics, as well as by the heterogeneity in sequencing platforms, applications and protocols. Here we present the genome comparison and analyt...

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