BACKGROUND: Hypertensive disorders in pregnancy are leading causes of maternal, fetal and neonatal morbidity and mortality worldwide. However, studies attempting to quantify the effect of hypertension on adverse perinatal outcomes have been mostly conducted in tertiary centres. This population-based study explored the frequency of hypertensive disorders in pregnancy and the associated increase ...

Spontaneous hepatic rupture, which is a complication of hypertension in pregnancy, is extremely rare. However, high maternal and perinatal mortality rates are observed. Moreover, it is frequently associated with severe preeclampsia or HELLP syndrome (a group of symptoms that include hemolytic anemia, hepatic enzyme increase, and thrombocytopenia). About 80% of the cases involve women who are in...

Aim: To compare mean serum calcium levels in pregnancy, with and without pregnancy induced hypertension. Study design: A Cohort study was done. Place duration of study: Department Obstetrics Gynaecology, Sir Ganga Ram Hospital, Lahore Unit III, from 1st January 2021 to 30th June 2021. Methodology: Two hundred patients gestational age between 28 40 weeks, were included the present study, 100 gro...

Pregnancy-induced hypertension (PIH), which includes both gestational hypertension and preeclampsia, is a common and morbid pregnancy complication for which the pathogenesis remains unclear. Emerging evidence suggests that insulin resistance, which has been linked to essential hypertension, may play a role in PIH. Conditions associated with increased insulin resistance, including gestational di...

preeclampsia is a major cause of morbidity and mortality during pregnancy. several independent investigators have demonstrated the association of androgens with hypertension. the main purpose of this study was to determine whether maternal levels of sex hormones, especially testosterone, are higher in patients with preeclampsia than in matched normotensive control subjects. serum levels of test...

objective: to compare maternal complications and labor outcome in obese and non-obese women. materials and methods: it is a retrospective comparative study conducted at the department of obstetrics and gynecology, unit 1, civil hospital, karachi from december 2008 to december 2009. a sample size of 220 gravid women is selected by non probability convenience sampling technique. in these 110 obes...

BACKGROUND Preeclampsia is a life-threatening pregnancy syndrome of uncertain origin. To elucidate the pathogenesis, we evaluated the temporal relationships between changes in vascular function and circulating biomarkers of angiogenic activity before and after the onset of preeclampsia and gestational hypertension. METHODS AND RESULTS Maternal mean arterial pressure, uterine artery pulsatilit...