Objective: Although frequently regarded as a low grade malignancy, basal cell carcinoma (BCC) sometimes shows aggressive behavior. Giant BCC is defined as a lesion greater then 5 centimeter. Material and Methods: The authors described the diagnosis and treatment protocol of giant BCC, involving lumbosacral region without any local or distant metastasis. Also the authors went through a thorough...

INTRODUCTION Osteoclast-like giant cells have been noted in various malignant tumors, such as, carcinomas of pancreas and liver and leiomyosarcomas of non-cutaneous locations, such as, uterus and rectum. We were unable to find any reported case of a leiomyosarcoma of the skin where osteoclast-like giant cells were present in the tumor. CASE PRESENTATION We report a case of a 59-year-old woman...

BACKGROUND Haemangiomata are the most frequent benign solid liver lesion. The management of giant (> or =5 cm) haemangiomata of the liver remains controversial. METHODS A search of relevant peer-reviewed literature was conducted using PubMed and original articles were reviewed. RESULTS AND CONCLUSIONS The vast majority of giant haemangiomata remain asymptomatic and have a benign and uncompl...

Extrinsic systems were shown to control the excitability of the neurones which mediate tail-flip escape in the crayfish. Restraint suppresses the escape mediated by giant fibres and some, but not all, categories of non-giant mediated escape; autotomy of claws increases the excitability of non-giant mediated escape without affecting the lateral giant reflex. The effects of restraint on the later...

Acetylcholine is the major excitatory neurotransmitter in the central nervous system of insects. Mutant analysis of the Dalpha7 nicotinic acetylcholine receptor (nAChR) of Drosophila shows that it is required for the giant fiber-mediated escape behavior. The Dalpha7 protein is enriched in the dendrites of the giant fiber, and electrophysiological analysis of the giant fiber circuit showed that ...

BACKGROUND Giant cell fibroma is a type of fibrous tumour of the oral mucosa which rarely affects children under the age of 10. The purpose of this paper was to contribute two clinically and histologically documented cases of giant cell fibroma in the free gingiva of a 7 and 6 year old boys. METHODS Both nodules were presented in the mandibular anterior region. In the differential diagnosis s...

For the eclipsing symbiotic binary FG Ser (AS 296) we have obtained a series of high resolution optical spectra. Combining the measured radial velocity variations for the red giant with published eclipse photometry gives a binary period of 650 days. We derive the radial velocity curve of the red giant, yielding the orbital parameters of the system and a mass function of mf = 0.039 M . We furthe...