By Sephadex LH-20 gel chromatography of an extract from Gingko biloba leaves, polymeric proanthocyanidins were eluted after the fractions of flavonol glycosides and biflavone glycosides. A purified proanthocyanidin polymer accounted for 86.6% of the total proanthocyanidins, and for 37.7% of the total antioxidant activity of this leaf extract. For structure elucidation, the polymer was submitted...

Ginkgo biloba (EGb 761) as a phytotherapeutic agent used in otoneurology, psychiatry, and ophthalmology. We studied the efficacy of therapy with EGb 761 in 72 patients (44 male and 28 female) with chronic cochleovestibular disorders. We used pure-tone audiology, measuring pure-tone average, speech reception threshold, and speech discrimination score. Then we used craniocorpography to measure la...

The case of a 56 year old man who suVered a spontaneous intracerebral haemorrhage after regular self medication with the herbal preparation, Ginkgo biloba leaf extract is described, and the possible association is discussed. (Postgrad Med J 2001;77:112–113)

As the body ages, free radical processes intensify and risk of various age-related diseases increases, including memory impairment, as exchange in nerve cells deteriorate. The internal antioxidant system, capable neutralizing radicals, is not always able to cope with growing load, then supply antioxidants from outside necessary. A source biologically active substances possessing activity are pl...

Effect of administration of the standardized extract of Ginkgo biloba leaves (EGb 761) on learning, memory and exploratory behavior was estimated in water maze and hole-board tests. Rats (18-month old) received for three months EGb 761 at doses: 50, 100 and 150 mg/kg b.w. per day. After completion of the behavioral experiment, concentrations of neurotransmitters were estimated in selected brain...

The numbers of marketing claims and food, beverage, and drug products claiming to increase mental energy have risen rapidly, thus increasing the need for scientific specificity in marketing and food label claims. Mental energy is a three-dimensional construct consisting of mood (transient feelings about the presence of fatigue or energy), motivation (determination and enthusiasm), and cognition...

The prevalence of degenerative disorders in public health has promoted in-depth investigations of the underlying pathogenesis and the development of new treatment drugs. Ginkgo biloba leaves extract (EGb) is obtained from Ginkgo biloba leaves and has been used for thousands of years. In recent decades, both basic and clinical studies have established the effects of EGb. It is widely used in var...

habit (Tamara Crupi, September 1996) LOCAL NAMES Chinese (ya-chiao,ginkyo,ginnan,pakgor su,paikua su,yinxing,gong sun shu,icho,fozhijia); Dutch (Japanse notenboom,waaierboom,tempelboom,ginkgo); English (ginkgo,Kew tree,golden fossil tree,maiden-hair tree); French (arbre des pagodes,arbre de Gordon,noyer du Japon,ginkgo,ginkgo bilobé,arbre aux quarante ecus,arbre à noix); German (ginko,entenfuss...

Autumnal tints are one of the most manifest and fascinating natural phenomena, but the mechanism of chlorophyll (Chl)-breakdown in deciduous trees has not been fully elucidated. In this study, we analyzed the composition of Chl-related compounds and determined the activities of initial Chl-degrading enzymes in Ginkgo leaves at various stages in the process of autumnal coloring. Only pheophytin ...