The correlation between tubocurarine requirements and the electrophoretic serum protein pattern was investigated in 52 adult patients undergoing upper abdominal surgery under nitrous oxide and oxygen anaesthesia. There was a positive correlation between the tubocurarine requirements (mg/kg) and the serum level of gamma globulin; r = +0.604, which is highly significant (P<0.001). This correlatio...

Hepatitis A (HAV) causes one of the most common infectious diseases in the world and may produce clinical conditions ranging from a-symptomatic infection to acute liver failure. Hepatitis A infection is an endemic problem in most African and South American Countries, meanwhile its incidence has largely declined over the last 2 decades in Western Europe and USA [1, 2]. The traditional preventive...

The rat alpha 2u globulin gene family encodes approximately 20 low-molecular-weight (20,000) proteins with pIs ranging from 4.5 to 7.9. alpha 2u globulin protein isoforms were detected in the liver and in the submaxillary, lachrymal, preputial, and mammary glands of Sprague-Dawley rats. The hormonal and developmental regulation of alpha 2u globulin synthesis in each of these tissues was unique,...

the study on the serum protein electrophoresis following thyroidectomy in a puppies showed a significant decrease in the albumin and -a-ratio associated with a relative increase in gamma and total globulin, but alterations of alpha i and beta globulin were not statistically charcteristic in our thyroidectomized dogs.

Antibody and y-globulin are formed by a number of tissues with highly heterogeneous cell populations such as bone marrow, lymph glands and spleen. Only a small part of the cells in these tissues are plasma-type celLs in which antibody protein and at least some ofthe y-globulin normally found in serum originate. This makes a study of globulin synthesis difficult. Recently, Dr M. Potter and his c...