OBJECTIVE Peripheral lower body fat is associated with lower cardiometabolic risk. Physiological differences in gluteal compared with abdominal subcutaneous (sc) adipocyte functions are known but the molecular basis for depot differences in adipocyte function is poorly understood. Our goal is to identify novel gene regulatory pathways that underlie the heterogeneity of human fat distribution. ...

STUDY DESIGN Controlled laboratory study, repeated-measures design. OBJECTIVES To compare hip abductor muscle activity during selected exercises using fine-wire electromyography, and to determine which exercises are best for activating the gluteus medius and the superior portion of the gluteus maximus, while minimizing activity of the tensor fascia lata (TFL). BACKGROUND Abnormal hip kinema...

Pentazocine has been one of the commonly abused injectable prescription opioids associated with dermatological complications. We present the case of a 43-year-old male who presented to us with bilateral gluteal pyomyositis and multiple sinus tracts as a consequence of pentazocine abuse. The patient had been given injectable pentazocine for relief of his migrainous headache by his local physicia...

PURPOSE OF THE STUDY Gluteal muscle contracture (GMC) is a chronic fibrotic disease of gluteal muscles which is characterized by excessive deposition of collagen in the extracellular matrix. Transforming growth factor (TGF)-βs have been shown to play an important role in the progression of GMC. However, the underlying mechanisms are not entirely clear. We sought to explore the expression of TGF...

Acute gluteal artery syndrome secondary to superior gluteal artery injury following pelvic fracture is a rare entity with potential for significant morbidity and mortality. In this report we present such a case resulting with a favorable outcome with prompt diagnosis and appropriate treatment.

Introduction Dermal fillers are used for multiple cosmetic indications including gluteal and thigh augmentation. Complications, although infrequent, are increasing due to the dramatic growth of dermal filler use. Our aim was to describe how the complication of infected silicone granulomas can present following lower limb augmentation. Methods Two cases presented with pain, oedema, and erythem...

OBJECTIVE To compare the regional differences in subcutaneous adipose tissue hormone/cytokine production in abdominally obese women during weight loss. METHODS Forty-two abdominally obese, older women underwent a 20-week weight loss intervention composed of hypocaloric diet with or without aerobic exercise (total energy expenditure: ∼2800 kcal/week). Subcutaneous (gluteal and abdominal) adipo...

Pioneering epidemiological work has established strong association of sedentary lifestyle and obesity with the risk of colorectal cancer, while the detailed underlying mechanism remains unknown. Here we show that Hotair (HOX transcript antisense RNA) is a pro-adipogenic long non-coding RNA highly expressed in gluteal-femoral fat over other fat depots. Hotair knockout in adipose tissue results i...

OBJECTIVES This study investigated changes in craniocervical and trunk flexion angles and gluteal pressure on both sides during visual display terminal (VDT) work with continuous cross-legged sitting. METHODS The gluteal pressures of ten VDT workers, who were recruited from laboratories, were measured using a Teckscan system and videotaped using a single video camera to capture the craniocerv...