BACKGROUND Myomectomy has potential risks of complications. To reduce these risks, medical pre-treatment can be applied to reduce fibroid size and thereby potentially decrease intra-operative blood loss, the need for blood transfusion and emergency hysterectomy. The aim of this systematic review and meta-analysis is to study the effectiveness of medical pre-treatment with Gonadotropin-releasing...

Utero-ovarian arterial blood flow and hormonal profile were evaluated in 20 patients with polycystic ovary syndrome (PCOS) and in 22 patients with normal menstrual cycle (NMC) undergoing in-vitro fertilization (IVF) treatment. In this controlled prospective clinical study the vascular impedance in the utero-ovarian arteries was measured in both groups on days 4, 13, 22 [introduction of gonadotr...

The effectiveness of two kinds of dopamine antagonist (DA), metoclopramide (Met) and domperidone (Dom) combined with the gonadotropin releasing hormone analogue (D-Ala6, Des Gly10 ethylamide) GnRHa was assayed on the ovulation success, latency period, ovulation index (OI) and fertilization success of kutum, Rutilus frisii kutum (Kamenskii, 1901). Brood fish were injected intra-peritoneally as f...

In this study, the benefits of using the first Iranian made GnRHa[D-Ala6 des Gly10] mGnRH ethylamide, to induce spermiation in male rainbow trout, Oncorhynchus mykiss, were evaluated, In addition, its effect on acceleration and synchronization, quality and quantity of milt and the plasma Testosterone (T) fluctuations were examined. For these purposes, 40 non-spermiating male rainbow trouts were...

Gonadotropin-releasing hormone agonist (GnRHa) peptide drugs including leuprolide and deslorelin have been successfully used for decades in humans, domestic animals, free-ranging wildlife and animals in zoological facilities, and more recently in avian and exotic companion animals. Typical uses for GnRHa include reproductive stimulation, reproductive suppression (contraception or hormonerespons...

Methods Clinical Records of 17 children (16 girls and 1 boy) were retrospectively analyzed over a period of 24 months (Mar 2012 to Mar 2014). All children satisfied the criteria for precocity based on clinical features, radiological assessment and GnRHa stimulation test. All 16 girls had idiopathic precocious puberty and the only boy had hypothalamic hamartoma. The mean age of presentation was ...

BACKGROUND It is important to differentiate central from peripheral causes of precocious puberty because of distinct management options. CASE CHARACTERISTICS 4 girls with discordant pubertal development. OBSERVATIONS All had low basal and GnRHa stimulated FSH and LH level with high estradiol level. Abdominal ultrasonogram helped in diagnosing precocious pseudopuberty- ovarian cyst in 3 chil...

Adolescents with gender dysphoria experience incongruence between their assigned and their experienced gende [1]. Gender reassignment therapy aims to achieve transition to the desired gender and includes psychological, hormonal and surgical interventions. Puberty can be suspended using gonadotropin releasing hormone analogues (GnRHa) thus preventing development in the direction of the natal gen...

Introduction Uterine fibroids are the most common benign tumor in women in Kazakhstan. In the past two decades, endoscopic surgery has played an important role in the development of gynecologic surgery, particularly in the treatment of uterine fibroids. The goal of this paper is to evaluate whether uterine artery embolization (UAE) or gonadotropin-releasing hormone agonists (GnRHa) prior to myo...