Developing countries, where malaria is one of the most prevalent diseases, still rely on traditional medicine as a source for the treatment of this disease. For the present study, Trigonella foenum-graecum L. (fenugreek) were collected from Coimbatore, Tamilnadu, India. The test plant has been used in India by traditional healers for the treatment of fever as well as other diseases. The active ...

The objective of the present investigation was to study antidiabetic activity of standardized extract of Trigonella foenum-graecum seeds (IND01) using neonatal streptozotocin-induced rat (n-STZ) model of diabetes mellitus (DM) in rats for the first time. Streptozotocin (STZ) was injected (50 mg/kg i.p.) in pups of rats in a split dose manner (on 2nd and 3rd postnatal days). After 8 weeks, DM wa...

The present investigation was undertaken to evaluate antioxidative property of fenugreek seed extract (FSE) on lipid peroxidation and fluorescence product in salivary glands of mice. The aging was induced by D-galactose (Dg). Adult albino male mice (Mus musculus L) were divided into four groups viz. 1)Control group received subcutaneous injection of 0.5 ml sterile water/day for 20 days 2) Dgtre...

effects of salinity and drought on growth, contents of proline, malondialdehyde (mda), proteinand activity of antioxidative enzymes were studied in two trigonella species. seeds andexplants of t. foenum-graecum and t. aphanoneura were grown on murashige and skoogmedium (ms) complemented with iso-osmotic concentrations of nacl (0, 100, 150 mm) andmannitol (0, 180, 275 mm). growth and relative wa...

This study investigated the inhibitory effect of aqueous extract of Trigonella foenum-graecum seeds (AqE-TFG) on fat accumulation and dyslipidemia in high fat diet- (HFD-) induced obese rats. Female Wistar rats were fed with HFD ad libitum, and the rats on HFD were treated orally with AqE-TFG or orlistat ((HFD for 28 days+AqE-TFG (0.5 and 1.0 g/kg) or orlistat (10 mg/kg) from day 8 to 28), resp...

Alzheimer's disease (AD) is the most common form of dementia that mainly affects the cognitive functions of the aged populations. Trigonella foenum-graecum (L.) (fenugreek), a traditionally well utilized medicinal plant ubiquitously used as one of the main food additive worldwide, is known to have numerous beneficial health effects. Fenugreek seed extract could be able to inhibit the activity o...