Grape seed extracts are commonly utilized as dietary supplements for their antioxidant properties, even from cancer patients. However, whether these natural extracts interfere with chemotherapeutics utilized in colon cancer treatment is still poorly investigated. The cytotoxicity of extracts from Italia and Palieri cultivars either alone or in combination with oxaliplatin was evaluated in colon...

Identifying the properties of the first generation of seeds of massive black holes is key to understanding the merger history and growth of galaxies. Mergers between ∼ 100M seed black holes generate gravitational waves in the 0.1–10Hz band that lies between the sensitivity bands of existing ground-based detectors and the planned space-based gravitational wave detector, the Laser Interferometer ...

background and aims. promoting remineralization is the ultimate goal of clinical prevention of caries lesion. the present in vitro study aimed to investigate the effect of grape seed extract (gse) on artificial enamel caries in primary human teeth. materials and methods. seventeen human sound primary incisors were sectioned mesiodistally. the tooth slices were placed in a demineralizing solutio...

thirty six wistar albino rats with implant induced endometriosis were randomly divided into six groups of six animals each. the rats in the first group received nothing and were euthanized at day 21. in the second group, rats received nothing and were euthanized at day 36. the third group received atorvastatin (atv; 5 mg kg-1 per day, orally) until 21 days from induction of endometriosis, and t...

BACKGROUND Inflammation and pain associated with temporomandibular joint disorder, a chronic disease that affects 15% of the adult population, involves activation of trigeminal ganglion nerves and development of peripheral and central sensitization. Natural products represent an underutilized resource in the pursuit of safe and effective ways to treat chronic inflammatory diseases. The goal of ...

BACKGROUND/AIM Therapeutic interventions in nonalcoholic fatty liver disease are limited, while anti-oxidative materials have shown benefits in animal models. This study aimed to evaluate grape seed extract as an anti-oxidative material in this process. Therapeutic effects of grape seed extract were evaluated in comparison to vitamin C in a double-blind setting. MATERIALS AND METHODS Fifteen ...

The aim of this study was to investigate the protective role of red grape seed extracts (GSEs) against oxidative damage on DNA, brain and erythrocytes in vitro. In this study, the protective effects of two GSEs (water and ethanol) on free radical mediated DNA-sugar damage, Fe -induced lipid peroxidation in brain and 2+ H O induced hemolysis and lipid peroxidation of erythrocytes were determined...

the purpose in this research was to study the effects of vermicompost and poultry manure on yield and yield components of the medicinal plant coriander (coriandrum sativum l.) in the shahr-e- ghods region. a factorial experiment using the randomized complete block design with three replications was conducted in the islamic azad university of shahr-e- ghods. the first factor was three levels of ...