نتایج جستجو برای: h2 receptor antagonists
تعداد نتایج: 636166 فیلتر نتایج به سال:
The general effects of cocaine are not well understood at the molecular level. What is known is that the dopamine D1 receptor plays an important role. Here we show that a key mechanism may be cocaine's blockade of the histamine H3 receptor-mediated inhibition of D1 receptor function. This blockade requires the σ1 receptor and occurs upon cocaine binding to σ1-D1-H3 receptor complexes. The cocai...
Dissociative charge exchange of CH5+ with Cs, coupled with quasiclassical trajectory calculations on an ab initio PES for CH5, has been used to probe the structure of the CH5+ cation. Product kinetic energy release distributions and branching ratios for CH5 --> CH4 + H and CH5 --> CH3 + H2 have been compared. The agreement of the product branching ratios provides evidence for the fluxional natu...
H2, the smallest and most abundant molecule in the universe, has a perfectly symmetric ground state. What does it take to break this symmetry? We found that the inversion symmetry can be broken by absorption of a linearly polarized photon, which itself has inversion symmetry. In particular, the emission of a photoelectron with subsequent dissociation of the remaining H+2 fragment shows no symme...
Modern computational methods have become so powerful for predicting the outcome for the H + H2 → H2 + H bimolecular exchange reaction that it might seem further experiments are not needed. Nevertheless, experiments have led the way to cause theorists to look more deeply into this simplest of all chemical reactions. The findings are less simple.
Hemodynamic responses to histamine were investigated in the anesthetized rabbit. Intravenous injections of histamine induced dose-dependent decreases in systemic arterial pressure that were blocked by the H1-receptor antagonist pyrilamine but not the H2 antagonist cimetidine. Injections of histamine and the H1 agonist 6-[2-(4-imidazolyl)ethylamine]- N-(4-trifuormethylphenyl)-heptanecardoxamide ...
The Garsia-Haiman modules are doubly graded modules for the symmetric groups, introduced by A. Garsia and M. Haiman [GH] to prove Macdonald’s positivity conjecture [M1]. These modules are defined for partitions of positive integers n, denoted by Dμ. The dimension of Dμ is given by n! whenever μ is a partition of n [H2]. As this fact implies, the Garsia-Haiman modules Dμ are isomorphic to the co...
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