Importance Since the accidental introduction of yellow-legged hornet (Vespa velutina nigrithorax) in France 2004, there have been reports this insect unexpectedly projecting a liquid toward human face, but ocular morbidity associated with is unknown, to our knowledge. Objective To describe case series lesions after exposure projection emitted by hornet. Design, Sett...

Background Tablet splitting can provide dose flexibility and cost savings; however, pharmaceutical representatives typically discourage the practice. Aim To identify summarise all published concerns related to tablet present experimental evidence that investigates those concerns. Design & setting Systematic review qualitative synthesis of tablet-splitting evidence...

AbstractObjectives Type 2 diabetes is a risk factor for sarcopenia. Evidence on the prevention of sarcopenia using blood glucose–lowering therapy limited. We aimed to examine relationship between changes in glycemic control and effect antidiabetic agents against patients with type diabetes. Design conducted an observational longitudinal study. Setting Participants...

ABSTRACTStudy Objective To characterize typical menstrual characteristics in a large sample of secondary school girls, as well knowledge (ie, normal) menstruation, endometriosis awareness, and educational needs. establish whether self-reported atypical period symptoms indicate suggesting the need for further clinical review specialist opinion. Design Cross-sectional s...

In the Chinese hamster cell line CHEF-125, sister chromatid exchanges occurred at a rate of a little higher than one per three chromosomes for each cell cycle. The exchanges were detectable by labeling with H(3)-thymidine and autoradiographic analyses of chromosomes at the second and subsequent metaphases after labeling had occurred. To test the hypothesis that sister chromatid exchanges are ca...

AbstractObjective To examine the mediating effects of food resource management skills (FRM) on relationship between participation in a Supplemental Nutrition Assistance Program Education (SNAP-Ed) nutrition education program and diet quality. Design Secondary analysis data from propensity score-matched sample participants (n = 396) nonparticipants 111) SNAP-Ed ...

Importance Black patients hospitalized with COVID-19 may have worse outcomes than White because of excess individual risk or are disproportionately cared for in hospitals all. Objectives To examine differences hospital mortality rates between and to assess whether the reflect patient characteristics by race which admitted. Design, Setting, Participants This cohort stu...

Background Myocardial fibrosis is an important adverse prognostic marker, however; determinants of myocardial in immune-mediated inflammatory diseases (IMIDs) remain poorly defined. Objectives To identify patients with IMIDs, as measured by cardiovascular magnetic resonance (CMR) extracellular volume (ECV). Methods Cross-sectional study 116 IMIDs undergoing clinical C...

Theoretical methods, such as molecular mechanics and dynamics, are very useful in understanding differences interactions at the single molecule level. In life sciences, small conformational changes, including substituent modifications, often have a significant impact on function vivo. Changes binding between nucleic acid molecules proteins prime example. this study, we propose strategy to predi...