Hair follicles (HF) undergo precisely regulated recurrent cycles of growth, cessation, and rest. The transitions from anagen (growth), to catagen (regression), to telogen (rest) involve a physiological involution of the HF. This process is likely coordinated by a variety of mechanisms including apoptosis and loss of growth factor signaling. However, the precise molecular mechanisms underlying f...

BACKGROUND Two drugs which are approved for the treatment of androgenetic alopecia in women in Germany were compared with regard to their influence on hair growth. PATIENTS AND METHODS Patients were randomized to group I (n = 52) who used 2% minoxidil solution twice daily for a period of 12 months or to group II (n = 51) who used 0.025% alfatradiol solution once daily for 6 months and were th...

Endocrine changes supervening after parturition and menopause participate in the control of sebum production and hair growth modulation. The ensuing conditions include some peculiar aspects of hair loss (effluvium), alopecia, and facial hirsutism. The hair cycling is of major clinical relevance because most hair growth disorders result from disturbances in this chronobiological feature. Of note...

Background: The Dermal Papilla (DP) consists in specialized dermal fibroblasts located at the base of hair follicles and secreting extracellular matrix, especially collagen and glycosaminoglycans. DP cells are responsible for the production of hair fibers, by inducing anagen phase, and by maintaining the hair in this growth phase. Miliacin (contained in millet oil) is known for its healing prop...

discussion: establishing the etiology, using the evidence–based strategies to improve hirsutism, and treating the underlying disorder, are essential for proper management of women with hirsutism. case presentation: the case was a 17-year-old female with severe hirsutism, oligomenorrhea, and obesity. she was evaluated to identify the etiology and diagnosed as a case of polycystic ovarian syndrom...

pathologic hair loss or even alopecia, was noticed. In the other 4 patients, hair was coming out in handfuls, leaving large areas of mutilating patchy alopecia. Those 4 patients reported that hair loss had begun approximately 6 weeks to 3 months after initiation of hemodialysis. We suspected that repeated anticoagulation with dalteparin, which shares many side effects with heparin,4 was respons...