Background: Smoking is a human behavior that has very bad impact on health. Mortality and morbidity due to smoking cannot be under­estimated. Non-communicable diseases become high among smokers, such as diabetes, reduced fertility, coronary heart disease, countless health complications. This study aims analyze the effect of use nicotine gum success cessation based number previous similar studie...

Background: Smoking is one of the most common causes of mortality in the world. Emotional intelligence is the adapting ability to respond to the environment and people appropriately. It plays an important role in various aspects of life such as facing stressful situations and consequently, smoking. This study aimed to investigate the relationship between nicotine dependency and emotional intell...

Background: Nicotine is a substance that can induce oxidative stress in the testes. And thus may reduce fertility in men. Antioxidant supplements such as curcumin can reduce oxidative stress and thus may increase fertility in men. Since the most active component responsible for the yellow color of turmeric and curcumin has anti-inflammatory and antioxidant properties. Therefore this study inves...

cartilage hair hypoplasia (chh), is a rare cause of metaphyseal chondrodysplasia and short stature. other features included hair abnormality, immunodeficiency, anemia, gastrointestinal disorders (hirschsprung disease, celiac, …) and increased risk of cancer. the disease is an autosomal recessive disorder and previously has not been reported in iran. we report a 9-year-old boy diagnosed as carti...

Much evidence indicates that individuals use tobacco primarily to experience the psychopharmacological properties of nicotine and that a large proportion of smokers eventually become dependent on nicotine. In humans, nicotine acutely produces positive reinforcing effects, including mild euphoria, whereas a nicotine abstinence syndrome with both somatic and affective components is observed after...

How different regimens of nicotine administration and withdrawal affect systemic inflammation is largely unknown. We studied the effects of chronic and acute nicotine administration and of nicotine withdrawal on the outcome of aseptic and septic systemic inflammation. Male C57BL/6 mice were implanted with subcutaneous osmotic pumps (to deliver nicotine) and intrabrain telemetry probes (to measu...

OBJECTIVE To evaluate the effectiveness of a lay delivered intervention to reduce Latino children's exposure to environmental tobacco smoke (ETS). The a priori hypothesis was that children living in households that were in the intervention group would have lower exposure over time than measurement only controls. DESIGN A two group, randomised control trial was conducted. SETTING Areas of Sa...

Objective: To evaluate the effectiveness of a lay delivered intervention to reduce Latino children’s exposure to environmental tobacco smoke (ETS). The a priori hypothesis was that children living in households that were in the intervention group would have lower exposure over time than measurement only controls. Design: A two group, randomised control trial was conducted. Setting: Areas of San...

In primates, nicotine is metabolically inactivated in the liver by CYP2A6 and possibly CYP2B6. Changes in the levels of these two enzymes may affect nicotine pharmacokinetics and influence smoking behaviors. This study investigated the independent and combined effects of ethanol self-administration and nicotine treatment (0.5 mg/kg b.i.d. s.c.) on hepatic CYP2A6 and CYP2B6 levels (mRNA, protein...