OBJECTIVE To explore the safety and effectiveness of treatment with the insulin analogue, biphasic insulin aspart 30 (BIAsp 30), in people with type 2 diabetes mellitus (T2DM) in a subgroup of a Pakistani population from the A1chieve study. METHODS A1chieve was a 24-week, international, prospective, multicentre, open label, observational, non-interventional study designed to evaluate the safe...

BACKGROUND/AIM The aim of this study, which included patients with insulin-dependent diabetes mellitus, was to determine the influence of the application of various treatment modalities (intensive or conventional) on the total plasma antioxidative capacity and lipid peroxidation intensity expressed as malondialdehyde (MDA) level, catalase and xanthine oxidase activity, erythrocyte glutatione re...

OBJECTIVES To assess whether type 2 diabetes mellitus (DM2) and DM2 complications are associated with presence and severity of depression among Alaska Native and American Indian people (AN/Als). DESIGN Retrospective, cross-sectional analysis of medical records. SETTING Southcentral Foundation Primary Care Center (SCF-PCC) in Anchorage, Alaska. PARTICIPANTS Total of 23,529 AN/AI adults. ...

OBJECTIVE To study the visual outcome in patients subjected to cataract extraction with prior grid laser and intraoperative intravitreal bevacizumab injection. METHODS This prospective case series comprised of 38 patients subjected to phacoemulsification and in the bag intraocular lens implantation at Al-Noor Eye Hospital and Sindh Govt Lyari General Hospital Karachi from January 2007 to Dece...

AIM The Physicians' Routine Evaluation of Safety and Efficacy of NovoMix 30 Therapy (PRESENT) study was done to assess the safety and effectiveness of biphasic insulin aspart 30 (BIAsp 30) in patients with type 2 diabetes mellitus in routine clinical practice. MATERIALS AND METHODS This was a prospective, multicentric, multinational, observational study in type 2 diabetes patients. The patien...

abstract background: production of advanced glycation end products (ages) is directly linked to the level and duration of hyperglycemia in diabetic patients. oxidative stress plays a major role in the pathogenesis of diabetes mellitus. free radicals are f01med in diabetes by glucose oxidation, nonenzymatic glycation of proteins and subsequent oxidative degradation of glycated proteins. thiobarb...

Allium hookeri (AH) has been used as a nutritional and medicinal food in Asia for many years. Our previous studies have described its anti-diabetic, anti-obesity, anti-inflammatory activities animal models prediabetes. This study investigated whether AH could improve glycemia by modulating insulin secretion prediabetic subjects through an in-depth study. Eighty (100 ≤ fasting plasma glucose &lt...