OBJECTIVE To investigate the differences in gene expression between children and adults with Kashin-Beck disease (KBD). METHODS 12 children with KBD and 12 healthy children were selected and divided into 4 KBD vs. control pairs matched according to age and gender, with each pair having 3 KBD children and 3 healthy children. Additionally, 15 adults with KBD and 15 healthy adults were selected ...

OBJECTIVE To evaluate the optimal interval for rechecking A1C levels below the diagnostic threshold of 6.5% for healthy adults. RESEARCH DESIGN AND METHODS This was a retrospective cohort study. Participants were 16,313 apparently healthy Japanese adults not taking glucose-lowering medications at baseline. Annual A1C measures from 2005 to 2008 at the Center for Preventive Medicine, a communit...

MRI lesions in younger healthy adults We have read with interest the article about CNS lesions in chronic inflammatory demye-linating polyneuropathy (CIDP).' The author's findings were based on clinical, electrophysiological, and MRI investigations. They found MRI lesions in nine of 21 patients under the age of 50. This age dependent analysis was introduced by the authors as it is well known th...

The interhemispheric coherence of electroencephalogram was studied in a group of healthy individuals in the age range of 20-50 years. The results showed higher coherence for all bands in parietal regions (P3-P4). It was observed that individuals with high values of coherence for a certain frequency band in a pair of electrodes also showed high values of coherence for other bands across other pa...

OBJECTIVE To estimate the prevalence and factors associated to healthy behavior among young adults. METHODS A total of 14,193 respondents aged 18-29 years who participated in the system Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico (VIGITEL--Telephone-Based Surveillance of Risk and Protective Factors for Chronic Diseases) carried out in 27 Brazilian ...

Much has been written by physicians about patients referred to them because of the discovery of a systolic murmur. Inevitably such consultant physicians have scant opportunity to judge the incidence, character, and significance of murmurs among apparently healthy people. Freeman and Levine (1933) described the systolic murmurs that they had found in a group they had examined of a thousand perso...

BACKGROUND AND OBJECTIVES We investigated the effect of different breathing aids on ventilation distribution in healthy adults and subjects with cystic fibrosis (CF). METHODS In 11 healthy adults and 9 adults with CF electrical impedance tomography measurements were performed during spontaneous breathing, continuous positive airway pressure (CPAP) and positive expiratory pressure (PEP) therap...

The present study evaluated subjective and objective cognitive measures as predictors of fluid intelligence in healthy older adults. We hypothesized that objective cognitive measures would predict fluid intelligence to a greater degree than self-reported cognitive functioning. Ninety-three healthy older (>65 years old) community-dwelling adults participated. Raven's Advanced Progressive Matrice...

Hemoglobin A 2 (HbA 2 ) was quantitated in blood from 212 healthy Pakistani adults with an age range of 16 to 60 years. HbA 2 level was observed in the range of 1.20 to 3.80% with mean ± SD as 2.67 ± 0.66% for both sexes. The mean level for males and females was 2.67 ± 0.66% and 2.66 ± 0.69% respectively. These values showed no significant difference (P > 0.1) among both sexes. The coefficient ...

Distortions of body image have often been investigated in clinical disorders. Much of this literature implicitly assumes healthy adults maintain an accurate body image. We recently developed a novel, implicit, and quantitative measure of body image - the Body Image Task (BIT). Here, we report a large-scale analysis of performance on this task by healthy adults. In both an in-person and an onlin...