نتایج جستجو برای: healthy tissue

تعداد نتایج: 1159786  

Journal: :Pharmacological reports : PR 2012
Anna Sadowska Bogusław Kędra Dariusz Cepowicz Lech Rodziewicz Anna Fiedorowicz Sławomir Prokopiuk Wojciech Miltyk Halina Car

BACKGROUND Metronidazole (MTZ) is indicated in the prevention of infections during surgical procedures. However, some data have shown that metronidazole has carcinogenic potential. METHODS In the present work, we determined concentrations of metronidazole and its hydroxy metabolite (MTZOH) in colorectal cancer patients. MTZ and MTZOH were measured in tumor tissue and surrounding healthy tissu...

Journal: :Genetic epidemiology 2017
Stephane Wenric Tiberio Sticca Jean-Hubert Caberg Claire Josse Corinne Fasquelle Christian Herens Mauricette Jamar Stéphanie Max André Gothot Jo Caers Vincent Bours

An increasing number of bioinformatic tools designed to detect CNVs (copy number variants) in tumor samples based on paired exome data where a matched healthy tissue constitutes the reference have been published in the recent years. The idea of using a pool of unrelated healthy DNA as reference has previously been formulated but not thoroughly validated. As of today, the gold standard for CNV c...

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