The incidence of major congenital defects is approximately 2.5% of total births. Congenital heart disease and neural tube defects each account for about onethird of all defects. From several studies in Europe and the United States it is estimated that the incidence of congenital heart disease is about seven cases per 1000 births (Lancet, 1975). As more than one cardiac lesion is sometimes prese...

Complex congenital heart defects (CHD) are associated with a variety of single gene abnormalities and chromosomal rearrangements. Of the various forms of CHD, aortic arch interruption, a conotruncal heart defect, is relatively uncommon. Here we report a male neonate with aortic arch interruption type B, secundum atrial septal defect, perimembranous ventricular septal defect, patent ductus arter...

Open heart surgery is rarely performed on patients with heart disease complicated by autoimmune hemolytic anemia (AIHA) with the aid of an artificial heart-lung machine. We successfully performed radical open heart surgery on an atrial septal defect (ASD) patient with the complication of AIHA.

In congenital cardiac surgery, intracardiac repair procedures like ventricular septal defect (VSD), atrioventricular and tetralogy of fallot (TOF) are associated with conduction system injury. Fewer cases reported describing life threatening complication late post-operative complete heart block. We reporting 2 patients who presented block after managed by permanent pacemaker placement in AFIC C...

The present study of 47 necropsy cases of congenital heart disease has revealed that cardiac defects occur as frequently in the African as in the non-African. The types of congenital heart disease and the associated non-cardiac malformations are similar to what has been described in non-Africans. Tetrad of Fallot was the commonest type of multiple defect and ventricular septal defect the most c...

49,xxxxy is rare chromosomal pattern and these patients have mental retardation, small penis, cryptorchidism and skeletal anomalies. we reported a 10 month-old boy who has hypotonia, microcephaly, hypertelorism, depressed nasal bridge, epicanthic folds and bilateral multiple ear tags, high arched palate, down set ears, micrognathia and congenital heart disease such as patent ductus arteriosus (...

Objective: To assess the clinical outcome of patients with isolated ventricular septal defects small enough not to require surgical closure. Methods: Between January 2001 and May 2003 a total of 118 patients who were recently or previously diagnosed to have isolated ventricular septal defects small enough not to require surgical closure were included in this study. Inclusion criteria for the st...