Soon after the sudden and simultaneous deaths of Francesco I de’Medici, Grand Duke of Tuscany, and his wife, Bianca Cappello, in October 1587, rumours spread that the two had been murdered by Francesco’s brother, Cardinal Ferdinando. 2 Apparently, Ferdinando had a very good motive to kill his brother and the woman that Francesco had loved and then married after the death of his first wife the G...

Johnson et al. (1996) presented evidence that Lake Victoria as dry before 12,800 C years ago. Broecker et al. (1998) oncluded from water-balance calculations that the precipitaion rate when the lake was dry must have been smaller than it s now by a factor of at least four. The apparent magnitude of he change in precipitation and its near simultaneity with other hanges elsewhere on the globe wer...

cute decompensated heart failure is among the most ommon indications for hospitalization in the U.S. and esults in approximately one million hospitalizations annully (1). Although consensus guidelines provide evidenceased strategies for the treatment of chronic heart failure, he current therapy of acute heart failure is largely empirical. he first priority of management is relief of symptoms. A...

In order to achieve interoperabiliiy among heterogeneous systems, markup languages such as XML and DAML are being used to describe distributed systems and data. The abiliiy lo successfully interoperate based on semantic markup depend on the abiliiy to create, use and manage shared onfologies of concepts and !heir interrelationships. Specifically, communicating systems in a nehvorked environment...

This paper presents an approach for monitoring several important aspects related to user behaviour during the execution of Web tasks. The approach includes the tracking of user interactions with the Web site and exploits visual data mining to highlight important information regarding Web application usage. In particular, our approach intends to be a natural heir of the approaches based on click...

In 1984 the Royal College of Surgeons in Ireland celebrates the 200th anniversary of the granting of its charter by George III in 1784. To mark this historic occasion the council of the college under the president, Professor Eoin O'Malley, will meet on 6 March 1984 in the board room of the Rotunda Hospital, where the first council sat with its president, Samuel Croker King. The bicentenary will...

In general, oxidative stress is defined as the imbalance between he production of reactive oxygen species (ROS) and reactive nitroen species (RNS) andantioxidantdefensemechanisms. These toxic olecules become highly reactive in their formation because of heir altered number of unpaired valence electrons. It corresponds o the mitochondria to be the main producer of ROS, generating he bulk of the ...

This paper presents an analysis of the extent to which tax planning affects the level of the inheritance tax rate that is perceived to be fair. In a factorial survey conducted in Germany, tax planning was found to increase the fair tax rate by approximately 4 percentage points. The fair tax rate is determined by not only the size of the bequest, the relationship of the heir to the bequeather, a...

I have reason to believe that Indians of the former class show little if any immunity from the ills to which the flesh of civilised man is heir. Only a few days ago I saw a case which illustrates this point. The patient was a Sikh, a forest officer who up to about two years ago had experienced fair health, though as his medical attendant wrote in his report of the case constipation had been his...

o the Editor: We thank Michael Bach and Steven Dakin and David rewther and Alexandra Sutherland for their interesting comentaries with regard to the technical issues associated with use f the Freiberg Visual Acuity and Contrast Test (FrACT) (version .3) (1) in our study (2). We chose the FrACT for use in our study, ecause it is both quick and easy to implement and provides us ith a quantitative...