نتایج جستجو برای: hemagglutinin gene

تعداد نتایج: 1147419  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Nicholas S R Sanderson Maria Zimmermann Luca Eilinger Céline Gubser Nicole Schaeren-Wiemers Raija L P Lindberg Stephanie K Dougan Hidde L Ploegh Ludwig Kappos Tobias Derfuss

Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) are associated with autoimmune central nervous system diseases like acute disseminated encephalomyelitis (ADEM). For ADEM, it is speculated that a preceding infection is the trigger of the autoimmune response, but the mechanism connecting the infection to the production of MOG antibodies remains a mystery. We reasoned that the abi...

Journal: :The Journal of biological chemistry 1975
S Toyoshima T Osawa

Two lectins were isolated from Wistaria floribunda seeds. One is a strong mitogen against human peripheal lymphocytes and has been purified in the previous paper (Toyo-Shima S., Y., Nakano K., Tonomura, A., and Osawa T. (1971) Biochemistry 10, 4457). The other, which is a strong hemagglutinin being devoid of mitogenic activity against normal lymphocytes, has been purified in this paper by affin...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Junfeng Liu David J Stevens Lesley F Haire Philip A Walker Peter J Coombs Rupert J Russell Steven J Gamblin John J Skehel

The viruses that caused the three influenza pandemics of the twentieth century in 1918, 1957, and 1968 had distinct hemagglutinin receptor binding glycoproteins that had evolved the capacity to recognize human cell receptors. We have determined the structure of the H2 hemagglutinin from the second pandemic, the "Asian Influenza" of 1957. We compare it with the 1918 "Spanish Influenza" hemagglut...

Journal: :Journal of periodontal research 2004
Joseph V Califano Debra Chou Janina P Lewis Jeffrey D Rogers Al M Best Harvey A Schenkein

BACKGROUND Porphyromonas gingivalis, a black-pigmented, gram-negative anaerobe, is found in periodontitis lesions and its presence in subgingival plaque significantly increases the risk for periodontitis. We have previously shown that patients with aggressive forms of periodontitis that are seropositive for P. gingivalis have less attachment loss than those that are seronegative. This suggests ...

Journal: :Microorganisms 2023

Influenza D virus (IDV) belongs to the Orthomyxoviridae family, which also include influenza A, B and C genera. IDV was first detected isolated in 2011 United States from pigs with respiratory illness. circulates mammals, including pigs, cattle, camelids, horses small ruminants. Despite broad host range, cattle are thought be natural reservoir of IDV. This plays a role as causative agent bovine...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Natalie Pica Rong Hai Florian Krammer Taia T Wang Jad Maamary Dirk Eggink Gene S Tan Jens C Krause Thomas Moran Cheryl R Stein David Banach Jens Wrammert Robert B Belshe Adolfo García-Sastre Peter Palese

After the emergence of pandemic influenza viruses in 1957, 1968, and 2009, existing seasonal viruses were observed to be replaced in the human population by the novel pandemic strains. We have previously hypothesized that the replacement of seasonal strains was mediated, in part, by a population-scale boost in antibodies specific for conserved regions of the hemagglutinin stalk and the viral ne...

2014
Andrew R. Dalby Munir Iqbal

A complete phylogenetic analysis of all of the H9N2 hemagglutinin sequences that were collected between 1966 and 2012 was carried out in order to build a picture of the geographical and host specific evolution of the hemagglutinin protein. To improve the quality and applicability of the output data the sequences were divided into subsets based upon location and host species. The phylogenetic an...

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