The case of an 81-year-old patient, initially presenting with gastrointestinal (GI) bleeding, including melena and hematemesis is reported. Endoscopy revealed an ulcerated mass of the stomach corpus with immunohistochemistry stains consistent with metastatic melanoma. The thorough physical and paraclinical examination did not reveal any lesions or nodules as a primary site of the disease. The l...

Acute esophageal necrosis is a rare cause of upper gastrointestinal bleeding, usually caused by hypoperfusion. In this report, we present a 34-year-old male patient suffering from acute esophageal necrosis presenting as hematemesis in a patient with Diabetic ketoacidosis. Diabetic ketoacidosis is rarely reported as a cause of acute esophageal necrosis and it is vital to diagnose it in a patient...

A 37 year old male with a history of peptic ulcer disease presented to the emergency room with nausea and vomiting. He reported two recent episodes of syncope, but denied other associated symptoms including palpitations, hematemesis, melena, chest pain, or dyspnea. He reported recent use of marijuana, but denied use of cocaine or methamphetamines. The patient reported similar symptoms in 2006 w...

Mucormycosis is an opportunistic infection caused by the fungi of the Mucorales order of the class Zygomycetes. Gastrointestinal mucormycosis is an uncommon, fatal condition accounting for only 7% of the cases. We present the case of a gastroduodenal mucormycosis presenting as recurrent massive hematemesis. We report this case to alert clinicians of this rare but fatal condition and to encourag...

Mallory-Weiss tears are mucosal lacerations caused by forceful retching and are typically located at the gastroesophageal junction. Mallory-Weiss tears have not been described in the duodenum. We report of a Mallory-Weiss tear in the descending duodenum of a 57-year-old man who presented with hematemesis preceded by forceful retching. We discuss the pathophysiology of a duodenal injury in compa...

Crimean-Congo hemorrhagic fever (CCHF) is a disease that poses a great threat to public health owing to its high mortality rate (30-70%), mode of transmission and geographic distribution. Here, we report on a nine years-old Sudanese boy from Southern Kordofan State who presented with Jaundice, high-grade fever, severe headache, abdominal pain and a history of hematemesis. The diagnosis of CCHF ...

Patients: 921 patients > 18 years of age (mean age 65 y, 68% men) who were hospitalized with severe, acute upper GI bleeding (hematemesis, bloody nasogastric aspirate, or melena). Exclusion criteria included massive exsanguinating or lower GI bleeding; recent trauma or surgery; Rockall score = 0 (low rebleeding risk) with hemoglobin (Hgb) level > 12 g/dL; or an acute coronary syndrome, symptoma...

Non-cirrhotic portal hypertension (NCPH) is a poorly understood condition attributed to various causes in the absence of liver cirrhosis. One important and rare conditions leading NCPH myeloproliferative neoplasms blood coagulation abnormalities, which infiltrate cells stasis raised sinusoidal pressure. We present case 40-year-old male who presented our emergency department with complaints hema...