نتایج جستجو برای: hematologic neoplasms
تعداد نتایج: 507542 فیلتر نتایج به سال:
Highlights from the 51st Annual Meeting of the American Society of Hematology, New Orleans, Louisiana, December 5-8, 2009.
Deep genomic sequencing technologies are beginning to resolve the underlying complexities of solid and hematologic cancers. Peter Nowell’s proposed model for cancer evolution suggesting that cancers evolve through branched evolutionary trajectories fuelled by genomic instability is now increasingly being accepted as a basis for therapeutic failure and the increasing mismatch between cost and cl...
A synchronous diagnosis of a plasma cell neoplasm (PCN) and non-plasma hematologic malignancy is very rare. We report what we believe the first instance PCN B lymphoblastic leukemia/lymphoma (B-ALL) diagnosed at initial presentation. The patient underwent laboratory evaluation for an underlying neoplasm, including immunology studies, bone marrow biopsy, flow cytometry immunophenotyping. Serum l...
We estimate the number of cases of hematologic malignancies expected to be newly diagnosed in the resident population of Sardinia during the year 2001, and classify the predicted cases according to disease, age and geographic distribution. The implications of these predictions for the Sardinian health care system are discussed, particularly with respect to the development of policies aimed to e...
Background: Hydroxyurea is administered to control elevated blood counts in patients with myeloproliferative neoplasms (MPNs) reduce the risk of thrombosis and mortality. We reviewed side effects hydroxyurea, development secondary malignancies, drug resistance observed some patients.Current Concepts: The low incidences malformed births, intrauterine deaths, spontaneous abortions associated hydr...
European Evidence-based Consensus: Inflammatory Bowel Disease and Malignancies Vito Annese,a Laurent Beaugerie,b Laurence Egan,c Livia Biancone,d Claus Bolling,e Christian Brandts,f Daan Dierickx,g Reinhard Dummer,h Gionata Fiorino,i Jean Marc Gornet,j Peter Higgins,k Konstantinos H Katsanos,l Loes Nissen,m Gianluca Pellino,n Gerhard Rogler,o Franco Scaldaferri,p Edyta Szymanska,q Rami Eliakim;...
No abstract available.
Aberrant activation of the JAK/STAT pathway has been reported in a variety of disease states, including inflammatory conditions, hematologic malignancies, and solid tumors. For instance, a large proportion of patients with myeloproliferative neoplasms (MPN) carry the acquired gain-of-function JAK2 V617F somatic mutation. This knowledge has dramatically improved our understanding of the pathogen...
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