The incidence of mechanical and infectious complications of totally implantable central venous access devices (TIDs) must be related to underlying disease, intensity of the chemotherapy, and frequency of manipulations. Records of the patients hospitalized from January 2002 to May 2005 were evaluated. Patients with TIDs were matched with patients without TIDs having the same malignancy and the s...

Cultured human bone marrow mesenchymal cells (MSCs) have immunomodulatory and tissue regenerative properties. This report summarizes the result of post-transplant treatment with MSCs of a 26-year-old patient with aplastic anemia complicated by invasive sino-orbital aspergillosis. The patient was treated with MSCs to benefit from the dual effects of MSCs in immune reconstitution: suppression aga...

Epstein-Barr Virus (EBV) causes a broad spectrum of disease in humans with several clinical syndromes and is ubiquitous, infecting more than 95% of the world's population. Central Nervous System (CNS) disease alone associated with Epstein-Barr virus rarely occurs in previously healthy individuals. Systemic viral illness in children and complications are rare, but may occur. In few cases, it is ...

BACKGROUND Sickle cell anemia (SCA) is a genetic hematological disorder characterized by red blood cells that assume abnormal, rigid, and sickle shape. The musculoskeletal complications of SCA result from vessel occlusion, leading to tissue ischemia and infarction and progressive end organ damage. AIM The aim of this study was to determine the pattern of musculoskeletal complications among ch...

this study evaluated the effects of mesobuthus eupeus (me) scorpion venom on inflammatory response following injection. additionally, the present study examined whether immunotherapy at specific time intervals would be effective on inflammatory response after me venom inoculation. animals were divided randomly into four groups: the first group received ld50 of venom and the second and third gro...

Results Thirty seven patients (36 f, 1 m) of SLE were reviewed.. The mean age at disease onset was 15 years with a range of 7-19 years. The most common features were mucocutaneus (malar rash in 84,8%, photosensitivity in 69,7%); musculoskeletal (arthritis in 87,9%) and hematological (leucopenia in 75,8%, anemia in 69,7%, Coombs test positive in 18,9% and, thrombocytopenia in 28%). Renal involve...

Rituximab is a chimeric anti-CD20 monoclonal antibody that is used to treat some hematological malignancies such as B-cell lymphomas, and various autoimmune diseases including immune thrombocytopenic purpura, systemic lupus erythematous, rheumatoid arthritis, and autoimmune hemolytic anemia. The most common side effects include fever, chills, and rigors. Respiratory complications such as cough,...

OBJECTIVE To investigate interferon (IFN) alpha 2 b for treating patients with JAK2V617F positive polycythemia vera (PV) and essential thrombocytosis (ET). METHODS Interferon alpha 2 b was used to treat patients with JAK2V617F positive PV and ET. In control group, hydroxyurea was used. Endpoint of study was to compare rates of hematological and molecular remission. RESULTS Patients in the i...

Aspirate and bone marrow biopsy are diagnostic methods used in the study of hematological diseases allowing molecular, cytogenetic, and immunophenotype analyses, indispensable today for the classification of hematolymphoid malignancies. Its indications are ample and include various types of hematolymphoid malignancies, solid tumors, study of fever of unknown origin, and other infiltrative disea...

Background: Although allogeneic hematopoietic stem cell transplantation (allo-HSCT) offers the possibility of cure for hematological malignancies, various complications have been described. Capillary leak syndrome (CLS) has been previously observed in HSCT patients. CLS is a rare disease characterized by recurrent episodes of generalized edema and severe hypotension along with hypoproteinemia. ...