conclusions hepatitis b core antibody immunoglobulin m positivity is different in healthy blood donors of different countries according to the prevalence of chronic hepatitis b and its vaccination. based on the current study findings, all positive samples of hepatitis b core antibody in iranian blood banks should be considered as candidates for occult hepatitis b not just the window period infe...

backgroung: hbv still continues to infect many people worldwide despite the availability of an effective vaccine for more than three decades. high prevalence of hbv may exist in high risk groups, particularly among intravenous drug users (idus). this group is among groups with higher risk of infection due to their hazardous behaviors such as sharing needle for drug injection. objectives: this c...

conclusions in conclusion, occult hbv was found in 36% of patients with negative results for hbsag, but positive results for hcv. detection of hbv-dna in both pbmcs and plasma together in comparison with plasma alone provided more true identification of obi.the svr rate was significantly higher in coinfected patients than mono-infected ones. background occult hepatitis b virus (hbv) infection (...

background as most hbv-related acute-on-chronic liver failure (aclf) have concurrent cirrhosis, it is important to clarify the association of viral factors with aclf with or without cirrhosis. objectives the aim of this study was to analyze the association of hbv genotypes and mutations with aclf development underlying different chronic liver diseases. patients and methods eighty-seven aclf pat...

background : drug injection is one of the most significant risk factors for viral hepatitis and human immunodeficiency virus (hiv) infection. the present study was performed to evaluate the frequency of hepatitis b (hbv) and hiv infection in idus and to identify the risk factors of these infections in this group in a central city of iran, shahre-kord. methods : this study was conducted in 2004 ...

background : hepatitis includes a wide range of clinical and pathological conditions. the beta-2 microglobulin (ãÿ2m), as part of thehla complex, is responsible for transmission of viral antigens on the surface of liver cells. the purpose of this study is to determine the concentration of salivary ãÿ2m as a marker of viral proliferation in subjects who are hbsag + , hbv dna pcr + compared with ...

background objectives: the risk of adefovir dipivoxil resistance emergence has increased in lamivudine-resistant hepatitis b infected patients. the mutations known as causing adefovir resistance, rtn236t and rta181v/t, are detected within the d and b functional domain of the hbv polymerase, respectively. in this study, we intended to determine the pre-existing adefovir-resistance mutations in p...

conclusions: premature stop codon in the s gene was observed in all countries with evaluable hbv genome sequences. co-existence of detectable hepatitis b surface antigen (hbsag) and s gene premature stop codon was inconsistent with other studies. investigations on yield truncated hbsag are suggested to determine if they can affect elisa hbsag results. background: we have previously reported on ...

background: despite the availability of an effective vaccine for more than three decades, hbv (hepatitis b virus) continues to infect many people worldwide, particularly in developing countries of asia. in older people at higher risk of infection, high prevalence of hbv may exist, particularly among intravenous drug users (idus). this group is among groups at higher risk of infection as they sh...