conclusions the prevalence of hbv infection among donors in duhok was comparable with those of reports from other parts of iraq. education and immunization should be initiated to target the high-risk groups. furthermore, a community-based study is recommended to study the prevalence of hbv and hcv infection in the population. background the prevalence of blood borne viral infection is escalatin...

conclusions the results showed a declining trend in anti-hbsab titers over the time after vaccination against hepatitis b virus in our region. further studies are warranted to establish the need for a booster dose in cases that are at risk of hepatitis b virus infection. results hepatitis b seroprotection rates (anti hbsab ≥ 10 iu/l) among vaccinated children and adolescents aged 1 and 18 years...

A frequent mutation at codon 97 of human hepatitis B virus core antigen has been shown to cause an "immature secretion" phenotype, featuring nonselective and excessive secretions of virions containing immature viral genome. Our current study demonstrates that this abnormality can be efficiently offset by another frequent core mutation, P130T.

Background and Aims: Evaluation of the prevalence of transfusion-transmissible infections (TTIs) in blood donors is a valuable index of donor selection and blood safety. This study was conducted to explore the prevalence and trends of TTIs markers and study of confidential unit exclusion )CUE) option among blood donors in Kurdistan province in the west of Iran. Materials and Methods: We conduc...

objective(s) the aim of this study was to characterize the hepatitis b virus surface protein genotypes and sequence variations among hepatitis b virus surface antigen (hbsag) positive chronic patients in hormozgan province, south of iran. materials and methods a total of 8 patients enrolled in this study. the surface gene was amplified and directly sequenced. genotypes and nucleotide/amino acid...

BACKGROUND Hepatitis E virus infection usually causes an acute and self-resolving hepatitis. In areas where chronic hepatitis B virus infection is prevalent, acute hepatitis E virus superinfection on chronic hepatitis B virus infection occurs sporadically. In recent years, however, chronic hepatitis E virus infection has been recognized in patients under immunosuppressant therapy. To the best o...

dna coding for the core antigen from hepatitis b virus (hbcag) was amplified, cloned and propagated in e. coli. the core protein was expressed in e. coli and the product was readily detected by western blot. this protein can be used as a diagnostic material in serum screening tests. to increase the level of expression of this antigen in bacteria, two plasmids were constructed in which the gene ...

occult hbv infection of hemodialysis (hd) patients is informative in terms of virus transmission. it may be of clinical importance in hd patients. the aim of this study was to investigate the prevalence of anti-hbc in the hd patients. number of 126 patients undergoing hemodialysis were included in this study from main hemodialysis units in yazd. hepatitis b surface antigens (hbsag), hepatitis b...

results it was found that the positive hepatitis b surface antigen (hbsag), the high baseline hbv dna level, the positive hepatitis b virus e antigen (hbeag), and an absent or low hepatitis b surface antibody (hbsab) titer prior to starting treatment are the most important viral risk factors. furthermore, rituximab, anthracycline, and different types of tnf-α inhibitors were identified as the h...